ArticleJournal of the American Society of Nephrology : JASN2018
Glycine Amidinotransferase (GATM), Renal Fanconi Syndrome, and Kidney Failure.
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Article in Journal of the American Society of Nephrology : JASN, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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0cells of the map it votes in
50citing papers in PubMed
11.2field-weighted citation impact, top 1% of its field
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
50 citing papers in PubMed, 90 citations in OpenAlex.
- A metabolomics-based molecular pathway analysis of how the sodium-glucose co-transporter-2 inhibitor dapagliflozin may slow kidney function decline in patients with diabetes.Diabetes, obesity & metabolism · 2020 · on this mapTrial
- Primary Mitochondrial-Disorders-Associated Nephropathy in Adulthood.Kidney international reports · 2026Review
- Maternal protein restriction programs the ageing kidney: Proteomic signatures of early-life origin renal and metabolic dysfunction.The Journal of physiology · 2026Article
- Metabolic and redox pathway dysregulation in HIV-associated coronary endothelial dysfunction.American journal of physiology. Heart and circulatory physiology · 2026Observational
- When X Does Not Mark the Spot: Autosomal Dominant and Recessive Forms of Renal Hypophosphatemic Rickets and Osteomalacia.Current osteoporosis reports · 2026Review
- Genetic Screening of Patients With Inherited Fanconi Syndrome.Kidney international reports · 2026Article
- GATM alleviates sepsis-induced acute kidney injury via PDK4-mediated glycolytic reprogramming in renal tubular epithelial cells.Cellular and molecular life sciences : CMLS · 2026Article
- Carrier screening in the reproductive setting-Are there medical implications for the heterozygote?-A guide for clinicians.Pregnancy (Hoboken, N.J.) · 2026Review
- Functional Analysis of a Novel Pathogenic Glycine Amidinotransferase Mutant in Hereditary Fanconi Syndrome.Kidney medicine · 2026Article
- Renal proteomic landscape of a patient with Fanconi renotubular syndrome carrying a novel GATM variant.Frontiers in physiology · 2026Article
- A puzzling renal Fanconi syndrome.Clinical kidney journal · 2025Article
- Guanidinylation of the cold shock protein YB-1: Molecular basis, structural changes and Notch-3 receptor binding.Protein science : a publication of the Protein Society · 2025Article
- Assessing Creatine-Related Gene Expression in Kidney Disease: Can Available Data Give Insights into an Old Discussion?Nutrients · 2025Review
- Kidney multiome-based genetic scorecard reveals convergent coding and regulatory variants.Science (New York, N.Y.) · 2025Article
- The role of mitochondria-related genes and immune infiltration in carotid atherosclerosis: identification of hub targets through bioinformatics and machine learning approaches.Frontiers in genetics · 2025Article
- Association between GATM gene polymorphism and progression of chronic kidney disease: a mitochondrial related genome-wide Mendelian randomization study.Scientific reports · 2024Article
- Article
- Reduced guanidinoacetate in plasma of patients with autosomal dominant Fanconi syndrome due to heterozygous P341LJIMD reports · 2024Article
- Blood metabolites and chronic kidney disease: a Mendelian randomization study.BMC medical genomics · 2024Article
- Ramipril therapy in integrin α1-null, autosomal recessive Alport mice triples lifespan: mechanistic clues from RNA-seq analysis.The Journal of pathology · 2024Article
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Authors and funding
54 authors at 18 institutions in 6 countries.
Markus ReicholdMedical Cell Biology.
Enriko D KlootwijkCentre for Nephrology and.
Joerg ReindersInstitute of Functional Genomics.
Edgar A OttoDivision of Nephrology and.
Mario MilaniItalian National Research Council (CNR), Institute of Biophysics, Milan, Italy.
Carsten BroekerMedical Cell Biology.
Chris LaingCentre for Nephrology and.
Julia WiesnerMedical Cell Biology.
Sulochana DeviDepartment of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, Michigan.
Weibin ZhouDepartment of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, Michigan.
Roland SchmittMedical Cell Biology.
Ines TegtmeierMedical Cell Biology.
Christina SternerMedical Cell Biology.
Hannes DoellererMedical Cell Biology.
Kathrin RennerDepartment of Internal Medicine III, and.
Peter J OefnerInstitute of Functional Genomics.
Katja DettmerInstitute of Functional Genomics.
Johann M SimbuergerInstitute of Functional Genomics.
Ralph WitzgallMolecular and Cellular Anatomy, University Regensburg, Regensburg, Germany.
Horia C StanescuCentre for Nephrology and.
Simona DumitriuCentre for Nephrology and.
Daniela IancuCentre for Nephrology and.
Vaksha PatelCentre for Nephrology and.
Monika MozereCentre for Nephrology and.
Mehmet TekmanCentre for Nephrology and.
Graciana JaureguiberryCentre for Nephrology and.
Naomi IsslerCentre for Nephrology and.
Anne KesselheimCentre for Nephrology and.
Stephen B WalshCentre for Nephrology and.
Daniel P GaleCentre for Nephrology and.ORCID 0000-0002-9170-1579
Alexander J HowieCentre for Nephrology and.
Joana R MartinsInstitute of Anatomy, University of Zurich, Zurich, Switzerland.
Andrew M HallInstitute of Anatomy, University of Zurich, Zurich, Switzerland.
Michael KasgharianDepartment of Pathology, Yale University, New Haven, Connecticut.
Kevin O'BrienNHGRI, National Institutes of Health, Bethesda, Maryland.
Carlos R FerreiraNHGRI, National Institutes of Health, Bethesda, Maryland.
Paldeep S AtwalMayo Clinic, Jacksonville, Florida.
Mahim JainDepartment of Bone and OI, Kennedy Krieger Institute, Baltimore, Maryland.
Alexander HammersKing's College London and Guy's and St. Thomas' PET Centre, London, United Kingdom.
Geoffrey Charles-EdwardsMedical Physics, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom.
Chi-Un ChoeDepartment of Neurology, University Hamburg, Hamburg, Germany.
Dirk IsbrandtDeutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Research Group Experimental Neurophysiology, Bonn, Germany, and University of Cologne, Cologne, Germany.
Alberto Cebrian-SerranoWellcome Centre for Human Genetics and.
Ben DaviesWellcome Centre for Human Genetics and.ORCID 0000-0003-3623-600X
Richard N SandfordDepartment of Medical Genetics, University of Cambridge, Cambridge, United Kingdom.
Christopher PughNuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
David S KoneckiGeneDX, Gaithersburg, Maryland; and.
Sue PoveyGenetics, Evolution and Environment, University College London, London, United Kingdom.
Detlef BockenhauerCentre for Nephrology and.ORCID 0000-0001-5878-941X
Uta Lichter-KoneckiDivision of Medical Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania.
William A GahlNHGRI, National Institutes of Health, Bethesda, Maryland.
Robert J UnwinCentre for Nephrology and.
Richard WarthMedical Cell Biology, richard.warth@ur.de r.kleta@ucl.ac.uk.ORCID 0000-0001-6084-0659
Robert KletaCentre for Nephrology and richard.warth@ur.de r.kleta@ucl.ac.uk.ORCID 0000-0002-0228-8656
Centre for Sight · INGenomics (United Kingdom) · GBNational Institutes of Health · USUniversity of Zurich · CHCentre for Human Genetics · GBUniversity of Michigan · USGuy's and St Thomas' NHS Foundation Trust · GBJacksonville College · USKennedy Krieger Institute · USKing's College London · GBNational Research Council · ITPediatric Nephrology of Alabama · USUniversität Hamburg · DEUniversity of Cologne · DEUniversity of Oxford · GBUniversity of Pittsburgh Medical Center · USUniversity of Regensburg · DEYale University · US
Funding
Human Biochemical GeneticsZIAHG000215 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI GAHL, WILLIAM · 2009 to 2025
$72.6MWellcome Trust
Abstract
PubMed holds no abstract for this paper.
Indexed as
AgedAmidinotransferasesAnimalsComputer SimulationFanconi SyndromeFemaleHeterozygoteHumansInfantInflammasomesKidney Failure, ChronicMaleMiceMice, KnockoutMitochondriaMolecular ConformationAmidinotransferasesglycine amidinotransferaseInflammasomesReactive Oxygen SpeciesAGATfibrosismitochondriopathyprotein depositstubulopathy
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What OpenQuestion holds
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.