ArticleJournal of the American Heart Association2018
Serum Magnesium Levels and Outcomes in Patients With Acute Spontaneous Intracerebral Hemorrhage.
Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association of magnesium intake with type 2 diabetes and total stroke: an updated systematic review and meta-analysis.BMJ open · 2020Pooled it
- The Effect of Magnesium Intake on Stroke Incidence: A Systematic Review and Meta-Analysis With Trial Sequential Analysis.Frontiers in neurology · 2019Pooled it
- Administration of Calcium and Magnesium in Acute Intracerebral Hemorrhage Patients: Assessing Safety and Feasibility.Journal of Korean medical science · 2025Trial
- Magnesium in Neurocritical Care: Clinical Relevance, Status Assessment, and Practical Implications for Outcomes-A Narrative Review.Nutrients · 2026Review
- Association of low magnesium status with incident intracranial hemorrhage: a matched-control database study.Frontiers in nutrition · 2026Article
- Prognostic value of day-of-event serum calcium and magnesium for predicting 1-year prognosis after intracerebral hemorrhage.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023Article
- Blood-Based Biomarkers in Intracerebral Hemorrhage.Journal of clinical medicine · 2023Review
- Initial Serum Magnesium Level Is Associated with Mortality Risk in Traumatic Brain Injury Patients.Nutrients · 2022Article
- Magnesium Sulfate and Cerebral Oxygen Saturation in Mild Traumatic Brain Injury: A Randomized, Double-Blind, Controlled Trial.Journal of clinical medicine · 2022Article
- Underlying microangiopathy and functional outcome of simultaneous multiple intracerebral hemorrhage.Frontiers in aging neuroscience · 2022Article
- Neuroprotective Therapies for Spontaneous Intracerebral Hemorrhage.Neurocritical care · 2021Review
- Observational
- Low Serum Magnesium Levels Are Associated With Hemorrhagic Transformation After Thrombolysis in Acute Ischemic Stroke.Frontiers in neurology · 2020Article
- Magnesium and Hemorrhage Volume in Patients With Aneurysmal Subarachnoid Hemorrhage.Critical care medicine · 2020Observational
- Article
- Magnesium: Pathophysiological mechanisms and potential therapeutic roles in intracerebral hemorrhage.Neural regeneration research · 2019Article
- Impact of Recent Studies for the Treatment of Intracerebral Hemorrhage.Current neurology and neuroscience reports · 2018Review
- The Role of Magnesium in Neurological Disorders.Nutrients · 2018Review
- Abnormal serum Magnesium Level is Associated with the Coagulopathy in Traumatic Brain Injury Patients.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMagnesium (Mg) has potential hemostatic properties. We sought to investigate the potential association of serum Mg levels (at baseline and at 48 hours) with outcomes in patients with acute spontaneous intracerebral hemorrhage (ICH). METHODS AND
resultsWe reviewed data on all patients with spontaneous ICH with available Mg levels at baseline, over a 5-year period. Clinical and radiological outcome measures included initial hematoma volume, admission National Institutes of Health Stroke Scale and ICH scores, in-hospital mortality, favorable functional outcome (modified Rankin Scale scores, 0-1), and functional independence (modified Rankin Scale scores, 0-2) at discharge. Our study population consisted of 299 patients with ICH (mean age, 61±13 years; mean admission serum Mg, 1.8±0.3 mg/dL). Increasing admission Mg levels strongly correlated with lower admission National Institutes of Health Stroke Scale score (Spearman's
conclusionsHigher admission Mg levels were independently related to lower admission hematoma volume and lower admission ICH score in patients with acute spontaneous ICH.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.