Evidence map›Paper›PMID 29654194›Full record

ArticleJournal of the American Heart Association2018

Specific Pharmacological Profile of A

Franck Paganelli, Noémie Resseguier, Marion Marlinge, Marc Laine, Fabrice Malergue, Nathalie Kipson, Pauline Armangau, Nicolas Pezzoli, Francois Kerbaul, Laurent Bonello and 4 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03218007 (A 2A Receptor), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03218007 nacompletednot on this map

A 2A Receptor (A2 AR) as a Novel Biomarkers for Physician Decision-making Improvement Evaluation's Patients With Suspected Acute Coronary Syndrome But Negative Troponin.

TypeinterventionalSponsorAssistance Publique Hopitaux De MarseilleRan2017 to 2019Enrolled83ConditionsAcute Coronary SyndromeArmsblood samples
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Pharmacological Profile of Adenosine AJournal of the American Heart Association · 2025
    Article
  3. Article
  4. Plasma ABiomedicines · 2022
    Article
  5. Review
  6. Article
  7. AFrontiers in cardiovascular medicine · 2021
    Article
  8. Homocysteine concentration and adenosine AJournal of cellular and molecular medicine · 2020
    Article
  9. Review
  10. Review
  11. Extracellular vesicles with ubiquitinated adenosine AJournal of cellular and molecular medicine · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Franck PaganelliDepartment of Cardiology, Hopital Nord, AP-HM, Aix-Marseille University, Marseille, France.
Noémie ResseguierChronic Diseases and Quality of Life Research Unit, EA 3279 Public Health, Aix-Marseille University, Marseille, France.
Marion MarlingeUMR MD2, Aix-Marseille University, Marseille, France.
Marc LaineDepartment of Cardiology, Hopital Nord, AP-HM, Aix-Marseille University, Marseille, France.
Fabrice MalergueUMR MD2, Aix-Marseille University, Marseille, France.
Nathalie KipsonUMR MD2, Aix-Marseille University, Marseille, France.
Pauline ArmangauDepartment of Cardiology, Hopital Nord, AP-HM, Aix-Marseille University, Marseille, France.
Nicolas PezzoliLaboratory of Biochemistry, Hopital Nord, AP-HM, Aix-Marseille University, Marseille, France.
Francois KerbaulSAMU, Marseille, France.
Laurent BonelloDepartment of Cardiology, Hopital Nord, AP-HM, Aix-Marseille University, Marseille, France.
Giovanna MottolaUMR MD2, Aix-Marseille University, Marseille, France.
Emmanuel FenouilletUMR MD2, Aix-Marseille University, Marseille, France.
Régis GuieuUMR MD2, Aix-Marseille University, Marseille, France guieu.regis@orange.fr.
Jean RufUMR MD2, Aix-Marseille University, Marseille, France.
Aix-Marseille Université · FRHôpital Nord · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe rapid and reliable exclusion of myocardial revascularization is a major unmet clinical need in patients with suspected coronary artery disease (CAD) and non-contributive electrocardiography and troponin. Non-invasive tests have high rates of false positives and negatives, and there is no biomarker to assess myocardial ischemia. The presence of spare adenosine A METHODS AND

resultsSixty patients with suspected CAD, but non-contributive electrocardiography and troponin, were consecutively enrolled in this prospective study. The binding (K

conclusionsIn patients with suspected CAD and non-contributive electrocardiography and troponin, the absence of spare A CLINICAL

trial registrationURL: http://www.clinicaltrials.gov. Unique identifier: NCT03218007.

Indexed as

ElectrocardiographyAgedBiomarkersCoronary AngiographyCoronary Artery DiseaseCoronary VesselsExercise TestFemaleFollow-Up StudiesFractional Flow Reserve, MyocardialHumansMalePrognosisProspective StudiesReceptor, Adenosine A2ATroponin IBiomarkersReceptor, Adenosine A2ATroponin Iadenosine receptorcoronary artery diseasediagnosis

Identifiers

PMID29654194
PMCPMC6015402
OpenAlexW2797504403

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.