Evidence map›Paper›PMID 29654190›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

Control of Excitation/Inhibition Balance in a Hippocampal Circuit by Calcium Sensor Protein Regulation of Presynaptic Calcium Channels.

Evanthia Nanou, Amy Lee, William A Catterall

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Presynaptic CabioRxiv : the preprint server for biology · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Generation of Sharp Wave-Ripple Events by Disinhibition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  14. Article
  15. Review
  16. Calcium Sensors in Neuronal Function and Dysfunction.Cold Spring Harbor perspectives in biology · 2019
    Review
  17. The Role of CaCell reports · 2019
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Evanthia NanouDepartment of Pharmacology, University of Washington, Seattle, Washington 98195 and.
Amy LeeDepartment of Molecular Physiology and Biophysics, University of Iowa, Iowa City, Iowa 52242.ORCID 0000-0001-8021-0443
William A CatterallDepartment of Pharmacology, University of Washington, Seattle, Washington 98195 and wcatt@uw.edu.
University of Washington · USUniversity of Iowa · US

Funding

Intellectual and Developmental Disabilities Research CenterU54HD083091 · NICHD · UNIVERSITY OF WASHINGTON · PI GARDEN, GWENN A · 2014 to 2019
$7.9M
MOLECULAR PROPERTIES OF VOLTAGE-SENSITIVE CHANNELSR01NS022625 · NINDS · UNIVERSITY OF WASHINGTON · PI CATTERALL, WILLIAM A · 1985 to 2019
$6.2M
Regulation of Neuronal Calcium ChannelsR01NS084190 · NINDS · UNIVERSITY OF IOWA · PI LEE, AMY · 2014 to 2018
$2.2M
NICHD NIH HHS U54 HD083091NINDS NIH HHS R01 NS022625NINDS NIH HHS R01 NS084190
6 · The paper itself

Abstract

Activity-dependent regulation controls the balance of synaptic excitation to inhibition in neural circuits, and disruption of this regulation impairs learning and memory and causes many neurological disorders. The molecular mechanisms underlying short-term synaptic plasticity are incompletely understood, and their role in inhibitory synapses remains uncertain. Here we show that regulation of voltage-gated calcium (Ca

Indexed as

AnimalsCA1 Region, HippocampalCA3 Region, HippocampalCalcium-Binding ProteinsCalcium ChannelsCalcium Channels, N-TypeCalcium SignalingFemaleHippocampusIn Vitro TechniquesMaleMiceNerve NetNeuronal Calcium-Sensor ProteinsNeuronal PlasticityPresynaptic TerminalsCa2+-binding protein-1Calcium-Binding ProteinsCalcium ChannelsCalcium Channels, N-TypeNeuronal Calcium-Sensor Proteinscalcium channelscalcium sensor proteinscalmodulinexcitation/inhibitionsneuro circuitsynaptic plasticity

Identifiers

PMID29654190
PMCPMC5932646
OpenAlexW2798137607

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.