Evidence map›Paper›PMID 29654173›Full record

ArticleBioscience reports2018

Evidence that the metabolite repair enzyme NAD(P)HX epimerase has a moonlighting function.

Thomas D Niehaus, Mona Elbadawi-Sidhu, Lili Huang, Laurence Prunetti, Jesse F Gregory, Valérie de Crécy-Lagard, Oliver Fiehn, Andrew D Hanson

Open access · goldAbstract read
In one paragraph

Article in Bioscience reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Biology · 2024
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  5. Review
  6. Review
  7. Article
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  9. Genome sequence and transcriptome profiles of pathogenic fungusComputational and structural biotechnology journal · 2021
    Article
  10. Article
  11. AIBP, Angiogenesis, Hematopoiesis, and Atherogenesis.Current atherosclerosis reports · 2020
    Review
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Thomas D NiehausHorticultural Sciences Department, University of Florida, Gainesville, FL, U.S.A. adha@ufl.edu tomniehaus@ufl.edu.
Mona Elbadawi-SidhuNIH West Coast Metabolomics Center, Genome Center, University of California Davis, Davis, CA, U.S.A.
Lili HuangFood Science and Human Nutrition Department, University of Florida, Gainesville, FL, U.S.A.
Laurence PrunettiMicrobiology and Cell Science Department, University of Florida, Gainesville, FL, U.S.A.
Jesse F GregoryFood Science and Human Nutrition Department, University of Florida, Gainesville, FL, U.S.A.
Valérie de Crécy-LagardMicrobiology and Cell Science Department, University of Florida, Gainesville, FL, U.S.A.
Oliver FiehnNIH West Coast Metabolomics Center, Genome Center, University of California Davis, Davis, CA, U.S.A.
Andrew D HansonHorticultural Sciences Department, University of Florida, Gainesville, FL, U.S.A. adha@ufl.edu tomniehaus@ufl.edu.
University of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NAD(P)H-hydrate epimerase (EC 5.1.99.6) is known to help repair NAD(P)H hydrates (NAD(P)HX), which are damage products existing as

Indexed as

ArabidopsisCatalytic DomainConserved SequenceEscherichia coliHumansMutationNADNADPPyridoxal PhosphateRacemases and EpimerasesSaccharomyces cerevisiaeStereoisomerismVitamin B 6NADNADPNAXE protein, humanPyridoxal PhosphateRacemases and EpimerasesVitamin B 6AIBPNAD(P)H hydratesNAD(P)HXNAXEprotein moonlightingVitamin B6

Identifiers

PMID29654173
PMCPMC5938422
OpenAlexW2796497679

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.