Evidence map›Paper›PMID 29654165›Full record

ArticleBioscience reports2018

Knockdown of the oncogene lncRNA NEAT1 restores the availability of

Yuliang Hu, Qiuyong Yang, Long Wang, Shuo Wang, Fei Sun, Dong Xu, Jian Jiang

Open access · goldAbstract read
In one paragraph

Article in Bioscience reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Emerging roles of long non-coding RNAs in osteosarcoma.Frontiers in molecular biosciences · 2024
    Review
  9. Cellular and Genetic Background of Osteosarcoma.Current issues in molecular biology · 2023
    Review
  10. Article
  11. Recent advances of NEAT1-miRNA interactions in cancer.Acta biochimica et biophysica Sinica · 2022
    Review
  12. Article
  13. Review
  14. Long Non-coding RNAs in Cisplatin Resistance in Osteosarcoma.Current treatment options in oncology · 2021
    Review
  15. Article
  16. Osteosarcoma and Metastasis.Frontiers in oncology · 2021
    Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yuliang HuDepartment of Orthopaedics, Zaozhuang hospital of Zaozhuang Mining Group, Zaozhuang, Shandong Province 277100, China.
Qiuyong YangDepartment of Orthopaedics, Zaozhuang hospital of Zaozhuang Mining Group, Zaozhuang, Shandong Province 277100, China.
Long WangDepartment of Orthopaedics, Affiliated Hospital of Xuzhou Medical College, Xuzhou, Jiangsu Province 221006, China.
Shuo WangDepartment of Orthopaedics, Zaozhuang hospital of Zaozhuang Mining Group, Zaozhuang, Shandong Province 277100, China.
Fei SunDepartment of Orthopaedics, Zaozhuang hospital of Zaozhuang Mining Group, Zaozhuang, Shandong Province 277100, China.
Dong XuDepartment of Orthopaedics, Zaozhuang hospital of Zaozhuang Mining Group, Zaozhuang, Shandong Province 277100, China.
Jian JiangDepartment of Orthopaedics, Affiliated Hospital of Xuzhou Medical College, Xuzhou, Jiangsu Province 221006, China jiangjian770218@163.com.
Zaozhuang Municipal Hospital · CNXuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aberrant expressions of long non-coding RNAs (lncRNAs) are the culprits of carcinogenesis via regulating the tumor suppressor or oncogene. LncRNA nuclear enriched abundant transcript 1 (NEAT1) has been identified to be an oncogene to promote tumor growth and metastasis of many cancers. However, the clinical significance and function of NEAT1 in osteosarcoma (OS) remain to be discovered. We here collected OS tissues (

Indexed as

AnimalsApoptosisCell Cycle CheckpointsCell Line, TumorCisplatinCyclin D1Drug Resistance, NeoplasmGene Expression Regulation, NeoplasticGene Knockdown TechniquesHumansMiceMicroRNAsOsteosarcomaProto-Oncogene Proteins c-bcl-2RNA, Long NoncodingRNA, Small InterferingBCL2 protein, humanCCND1 protein, humanCisplatinCyclin D1MicroRNAsMIRN34 microRNA, humanNEAT1 long non-coding RNA, humanProto-Oncogene Proteins c-bcl-2RNA, Long NoncodingRNA, Small InterferingCisplatinLncRNA NEAT1miR-34cOsteosarcomaResistance

Identifiers

PMID29654165
PMCPMC6435545
OpenAlexW2797352271

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.