Evidence map›Paper›PMID 29654044›Full record

ArticleBMJ open2018

Association between depressive symptoms and objectively measured daily step count in individuals at high risk of cardiovascular disease in South London, UK: a cross-sectional study.

Vera M Ludwig, Adam Bayley, Derek G Cook, Daniel Stahl, Janet L Treasure, Mark Asthworth, Anne Greenough, Kirsty Winkley, Stefan R Bornstein, Khalida Ismail

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Depression and Objectively Measured Physical Activity: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2020
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Vera M LudwigDepartment of Medicine III, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany.
Adam BayleyDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Derek G CookPopulation Health Research Institute, St George's, University of London, London, UK.
Daniel StahlDepartment of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Janet L TreasureSection of Eating Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Mark AsthworthDepartment of Primary Care and Public Health Sciences, King's College London, London, UK.
Anne GreenoughMRC & Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, UK.ORCID 0000-0002-8672-5349
Kirsty WinkleyDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Stefan R BornsteinDepartment of Medicine III, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany.
Khalida IsmailDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

Funding

Department of Health 10/62/03
6 · The paper itself

Abstract

objectivesDepressive symptoms are common but rarely considered a risk factor for unhealthy lifestyles associated with cardiovascular disease (CVD). This study investigates whether depressive symptoms are associated with reduced physical activity (PA) in individuals at high risk of developing CVD.

designSecondary analysis of the cross-sectional baseline data from a randomised controlled trial of an intensive lifestyle intervention.

setting135 primary care practices in South London, UK.

participants1742 adults, 49-74 years, 86% male at high (≥20%) risk of developing CVD in the next 10 years as defined via QRISK2 score. OUTCOME MEASURES: The main explanatory variable was depressive symptoms measured via the Patient Health Questionnaire-9 (PHQ-9). The main outcome was daily step count measured with an accelerometer (ActiGraph GT3X) stratified by weekdays and weekend days.

resultsThe median daily step count of the total sample was 6151 (IQR 3510) with significant differences (P<0.001) in mean daily step count between participants with low (PHQ-9 score: 0-4), mild (PHQ-9 score: 5-9) and moderate to severe depressive symptoms (PHQ-9 score: ≥10). Controlling for age, gender, ethnicity, education level, body mass index (BMI), smoking, consumption of alcohol, day of the week and season, individuals with mild depressive symptoms and those with moderate to severe depressive symptoms walked 13.3% (95% CI 18.8% to 7.9%) and 15.6% (95% CI 23.7% to 6.5%) less than non-depressed individuals, respectively. Furthermore, male gender, white ethnicity, higher education level, lower BMI, non-smoking, moderate alcohol intake, weekdays and summer season were independently associated with higher step count.

conclusionsPeople at high risk of CVD with depressive symptoms have lower levels of PA.

trial registrationISRCTN84864870; Pre-results.

Indexed as

AgedCardiovascular DiseasesCross-Sectional StudiesDepressionExerciseFemaleHumansLife StyleLondonMaleMiddle AgedRandomized Controlled Trials as TopicRisk Factorsadult psychiatrypublic healthsports medicine

Identifiers

PMID29654044
PMCPMC5898324

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.