Evidence map›Paper›PMID 29654010›Full record

ArticleBMJ open2018

Association between

Yinan Yao, Mei Liu, Feng Zang, Ming Yue, Xueshan Xia, Yue Feng, Haozhi Fan, Yun Zhang, Peng Huang, Rongbin Yu

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Current research status of HLA in immune-related diseases.Immunity, inflammation and disease · 2021
    Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Yinan Yao *Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China.
Mei Liu *Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China.
Feng Zang *Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China.
Ming YueDepartment of Infectious Diseases, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Xueshan XiaFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Yue FengFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Haozhi FanDepartment of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China.
Yun ZhangInstitute of Epidemiology and Microbiology, Huadong Research Institute for Medicine and Biotechnics, Nanjing, China.
Peng HuangDepartment of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China.ORCID 0000-0002-0146-921X
Rongbin YuDepartment of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China.
Nanjing Medical University · CNKunming University of Science and Technology · CNHuadong Hospital · CNJiangsu Province Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe

settingAll patients were recruited between January 2011 and September 2016 from the Jurong People's Hospital, Jiangsu Province, China.

participantsA total of 346 chronic hepatitis C (CHC) patients who finished the 48-week pegylated interferon-alpha and ribavirin (PEG IFN-α/RBV) treatment were enrolled in this study. All patients were former remunerated blood donors. The inclusion criteria for patients were as follows: (1) treatment-naive and treated with PEG IFN-α/RBV, (2) HCV RNA was present in serum for over 6 months before treatment, (3) negative for hepatitis B (HBV) or HIV infection and (4) lacked any other hepatic diseases.All participants in this study were Chinese Han population and infected with HCV genotype 1b and treated with subcutaneous PEG IFN-α at a dose of 180 µg once a week with the addition of 800-1000 mg/d RBV according to weight orally for 48 weeks.

resultsThe SNPs

conclusionGenetic variations at rs1044429, rs2284191 and rs2856997 were independent predictors of HCV treatment response in the Chinese Han population.

Indexed as

Antiviral AgentsChinaDrug Therapy, CombinationFemaleHepacivirusHepatitis C, ChronicHLA-D AntigensHumansInterferon-alphaMaleMiddle AgedPolyethylene GlycolsPolymorphism, Single NucleotideProspective StudiesRecombinant ProteinsRibavirinAntiviral AgentsHLA-D AntigensInterferon-alphapeginterferon alfa-2aPolyethylene GlycolsRecombinant ProteinsRibavirinchronic hepatitis Cgene polymorphismhla-dotreatmentvirological response

Identifiers

PMID29654010
PMCPMC5898346
OpenAlexW2796948424

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.