ArticleBlood2018
Patients with
Open access · bronzeAbstract read
In one paragraph
Article in Blood, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.
- Potential Pleiotropic Genes and Shared Biological Pathways in Epilepsy and Depression Based on GWAS Summary Statistics.Computational intelligence and neuroscience · 2022Pooled it
- SASH3 variants cause a novel form of X-linked combined immunodeficiency with immune dysregulation.Blood · 2021Trial
- Integrative proteogenomic and observational analysis identifies potential biomarkers for latent autoimmune diabetes in adults.Cardiovascular diabetology · 2026Observational
- mist: a hierarchical Bayesian framework for detecting differential DNA methylation dynamics in single-cell data.Nature communications · 2026Article
- Expanding the clinical spectrum of CD3γ deficiency: comprehensive characterization of adult-onset disease and integrated reevaluation of all reported patients.Frontiers in immunology · 2026Review
- Inborn errors of regulatory T-cell differentiation and function.The Journal of allergy and clinical immunology · 2025Review
- Single-cell transcriptomics reveals an abnormal immune microenvironment in plasma cell mastitis.Annals of medicine · 2025Article
- Monogenic inflammatory bowel disease: An unfolding enigma.World journal of clinical pediatrics · 2025Review
- TRIM13 prevents cardiomyocyte injury by affecting apoptosis through interacting with CD3D in myocardial infarction.iScience · 2025Article
- Preoperative MRI-based radiomics analysis of intra- and peritumoral regions for predicting CD3 expression in early cervical cancer.Scientific reports · 2025Article
- Genetic Associations of Clonal Hematopoiesis With Cardioembolic Stroke: Insights From Genome-Wide Mendelian Randomization, Bulk RNA, Single-Cell RNA Sequencing.CNS neuroscience & therapeutics · 2025Article
- Jurkat T-cell lines exhibit marked genomic instability affecting karyotype, mutational profile, gene expression, immunophenotype and function.Scientific reports · 2025Article
- Mapping the landscape of autoimmunity and autoinflammation in inborn errors of immunity: broad distribution with distinct clustering patterns.Frontiers in immunology · 2025Article
- Genetic Evaluation of the Patients with Clinically Diagnosed Inborn Errors of Immunity by Whole Exome Sequencing: Results from a Specialized Research Center for Immunodeficiency in Türkiye.Journal of clinical immunology · 2024Article
- Genomic characterization of peritoneal lavage cytology-positive gastric cancer.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2024Article
- Identification of unstable regulatory and autoreactive effector T cells that are expanded in patients withScience translational medicine · 2023Article
- Construction of the novel immune risk scoring system related to CD8Cancer cell international · 2023Article
- Could immune cells be associated with nephropathy in Fabry disease patients?International urology and nephrology · 2023Article
- Combining bioinformatics and machine learning algorithms to identify and analyze shared biomarkers and pathways in COVID-19 convalescence and diabetes mellitus.Frontiers in endocrinology · 2023Article
- A novel T-cell exhaustion-related feature can accurately predict the prognosis of OC patients.Frontiers in pharmacology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 6 institutions in 3 countries.
Jared H RoweDivision of Hematology-Oncology, Boston Children's Hospital, Boston, MA.
Ottavia M DelmonteLaboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.
Sevgi KelesDivision of Pediatric Immunology and Allergy, Meram Medical Faculty, Necmettin Erbakan University, Konya, Turkey.ORCID 0000-0002-4351-8200
Brian D StadinskiDepartment of Pathology, University of Massachusetts Medical School, Worcester, MA.ORCID 0000-0002-3831-6751
Adam K DobbsLaboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.ORCID 0000-0002-3432-3137
Lauren A HendersonDivision of Immunology, Boston Children's Hospital, Boston, MA.ORCID 0000-0001-6603-763X
Yasuhiro YamazakiLaboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.ORCID 0000-0002-1695-8614
Luis M AllendeDepartment of Immunology and.ORCID 0000-0001-9586-8539
Francisco A BonillaDivision of Immunology, Boston Children's Hospital, Boston, MA.ORCID 0000-0002-5553-2077
Luis I Gonzalez-GranadoPrimary Immunodeficiencies Unit, Department of Pediatrics, Hospital Universitario 12 de Octubre, Madrid, Spain.ORCID 0000-0001-6917-8980
Seyma Celikbilek CelikDivision of Pediatric Immunology and Allergy, Meram Medical Faculty, Necmettin Erbakan University, Konya, Turkey.
Sukru N GunerDivision of Pediatric Immunology and Allergy, Meram Medical Faculty, Necmettin Erbakan University, Konya, Turkey.ORCID 0000-0002-8860-6132
Hasan KapakliDivision of Pediatric Immunology and Allergy, Meram Medical Faculty, Necmettin Erbakan University, Konya, Turkey.
Christina YeeDivision of Immunology, Boston Children's Hospital, Boston, MA.ORCID 0000-0002-0025-6335
Sung-Yun PaiDivision of Hematology-Oncology, Boston Children's Hospital, Boston, MA.ORCID 0000-0002-0158-8147
Eric S HusebyDepartment of Pathology, University of Massachusetts Medical School, Worcester, MA.
Ismail ReisliDivision of Pediatric Immunology and Allergy, Meram Medical Faculty, Necmettin Erbakan University, Konya, Turkey.
Jose R RegueiroDepartment of Immunology, Complutense University School of Medicine, imas12 Research Institute, Madrid, Spain.ORCID 0000-0001-8442-7762
Luigi D NotarangeloLaboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.ORCID 0000-0002-8335-0262
Boston Children's Hospital · USNecmettin Erbakan University · TRNational Institutes of Health · USUniversity of Massachusetts Chan Medical School · USHospital Universitario 12 De Octubre · ESUniversidad Complutense de Madrid · ES
Funding
PATHOPHYSIOLOGY OF HUMAN BLOOD CELLST32HL007574 · NHLBI · CHILDREN'S HOSPITAL BOSTON · PI Daniel Evan Bauer · 1985 to 2026
$18.4MCharacterization of the cellular and molecular bases of inborn errors of immunityZIAAI001222 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI NOTARANGELO, LUIGI · 2017 to 2025
$15.2MT cell and transgenic core U19AI109858 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI HUSEBY, ERIC S · 2014 to 2018
$11.9MVirus induced immunopathologyR01AI081675 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI WELSH, RAYMOND M · 2009 to 2013
$2.0MNHLBI NIH HHS T32 HL007574NIAID NIH HHS R01 AI081675NIAID NIH HHS U19 AI109858NIAMS NIH HHS L40 AR065238
Abstract
Integrity of the T-cell receptor/CD3 complex is crucial for positive and negative selection of T cells in the thymus and for effector and regulatory functions of peripheral T lymphocytes. In humans,
Indexed as
ImmunomodulationMutationBiomarkersCD3 ComplexGene ExpressionHumansImmunophenotypingLymphocyte ActivationMultiprotein ComplexesProtein BindingReceptors, Antigen, T-CellT-Lymphocytes, RegulatoryT-Lymphocyte SubsetsBiomarkersCD3 antigen, gamma chainCD3 ComplexMultiprotein ComplexesReceptors, Antigen, T-Cell
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.