Evidence map›Paper›PMID 29653950›Full record

ReviewEuropean respiratory review : an official journal of the European Respiratory Society2018

Personalised medicine in interstitial lung diseases: Number 6 in the Series "Personalised medicine in respiratory diseases" Edited by Renaud Louis and Nicolas Roche.

Maria A Kokosi, George A Margaritopoulos, Athol U Wells

Abstract readReview
In one paragraph

Review in European respiratory review : an official journal of the European Respiratory Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Treatable Traits in Systemic Sclerosis.Clinical reviews in allergy & immunology · 2023
    Review
  8. Review
  9. Cardiopulmonary exercise testing in interstitial lung diseases and the value of ventilatory efficiency.European respiratory review : an official journal of the European Respiratory Society · 2021
    Review
  10. Article
  11. Article
  12. Identifying Biomarkers in Pediatric Rare Lung Disease. chILD Grows Up.American journal of respiratory and critical care medicine · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Maria A KokosiInterstitial Lung Disease Unit, Royal Brompton and Harefield NHS Foundation Trust, London, UK.
George A MargaritopoulosInterstitial Lung Disease Unit, Royal Brompton and Harefield NHS Foundation Trust, London, UK.
Athol U WellsInterstitial Lung Disease Unit, Royal Brompton and Harefield NHS Foundation Trust, London, UK.

Funding

Versus Arthritis 20719
6 · The paper itself

Abstract

Interstitial lung diseases in general, and idiopathic pulmonary fibrosis in particular, are complex disorders with multiple pathogenetic pathways, various disease behaviour profiles and different responses to treatment, all facets that make personalised medicine a highly attractive concept. Personalised medicine is aimed at describing distinct disease subsets taking into account individual lifestyle, environmental exposures, genetic profiles and molecular pathways. The cornerstone of personalised medicine is the identification of biomarkers that can be used to inform diagnosis, prognosis and treatment stratification. At present, no data exist validating a personalised approach in individual diseases. However, the importance of the goal amply justifies the characterisation of genotype and pathway signatures with a view to refining prognostic evaluation and trial design, with the ultimate aim of selecting treatments according to profiles in individual patients.

Indexed as

Precision MedicineAnimalsClinical Decision-MakingGene-Environment InteractionGenetic MarkersGenetic Predisposition to DiseaseHumansLife StyleLung Diseases, InterstitialMolecular Diagnostic TechniquesPatient SelectionPhenotypePredictive Value of TestsPrognosisRisk FactorsRisk Reduction BehaviorGenetic Markers

Identifiers

PMID29653950
PMCPMC9488852

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.