SynthesisBMC pregnancy and childbirth2018
A systematic review of non-antibiotic measures for the prevention of urinary tract infections in pregnancy.
Synthesis in BMC pregnancy and childbirth, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04832581 (Effectiveness Of The Self-Care Behavior Development Program For Urinary Tract Infections in Pregnant, Women), which is not on this map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness Of The Self-Care Behavior Development Program For Urinary Tract Infections in Pregnant, Women
Who cites it
16 citing papers in PubMed, 55 citations in OpenAlex.
- Efficacy of lactoferrin in preventing recurrent urinary tract infections in pregnant Egyptian women: a randomized controlled trial.BMC urology · 2025Trial
- Trial
- Exploring Non-antibiotic Interventions for Preventing Urinary Tract Infections During Pregnancy: A Systematic Review.Cureus · 2025Review
- The role of pharmacological interventions in managing urological complications during pregnancy and childbirth: A review.Medicine · 2025Review
- Urinary tract infection among pregnant Jordanian women: role of hygiene and sexual practices.BMC pregnancy and childbirth · 2024Article
- Short-chain fatty acids inhibit bacterial plasmid transfer through conjugationFrontiers in microbiology · 2024Article
- Changes in the Prevalence of Infection in Pregnant Women during the COVID-19 Lockdown.Microorganisms · 2023Article
- Prenatal and Perinatal Antibiotic Exposure and Long-Term Outcome.Pediatric gastroenterology, hepatology & nutrition · 2023Review
- Effectiveness of herbal medicines to prevent and control symptoms of urinary tract infections and to reduce antibiotic use: A literature review.Integrative medicine research · 2022Review
- Contribution of Symptomatic, Herbal Treatment Options to Antibiotic Stewardship and Microbiotic Health.Antibiotics (Basel, Switzerland) · 2022Review
- The immune responses to differentFrontiers in immunology · 2022Review
- Examination of Complementary Medicine for Treating Urinary Tract Infections Among Pregnant Women and Children.Frontiers in pharmacology · 2022Review
- Antibiotic Prescribing in Primary Care for Urinary Tract Infections (UTIs) in Pregnancy: An Audit Study.Medical sciences (Basel, Switzerland) · 2020Article
- 'There is no choice apart from antibiotics…': Qualitative analysis of views on urinary infections in pregnancy and antimicrobial resistance.Health expectations : an international journal of public participation in health care and health policy · 2020Article
- A Review of Micronutrients and the Immune System-Working in Harmony to Reduce the Risk of Infection.Nutrients · 2020Review
- Urinary tract infections and antibiotic use in pregnancy - qualitative analysis of online forum content.BMC pregnancy and childbirth · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundUrinary tract infections (UTIs) are common in pregnancy and account for the highest proportion of primary care antibiotic prescriptions issued to pregnant women in the UK. It is well known that antibiotic use is associated with increased antimicrobial resistance and therefore measures to minimise antibiotic use for UTI prevention have been studied. The efficacy and safety of these measures in pregnancy have not been addressed and therefore the aim of this study was to systematically review the literature to identify and evaluate potential measures to prevent UTIs in pregnant women.
methodsTen databases (EMBASE, AMED, BNI, CINAHL, Medline, PubMed, PsycINFO, Cochrane Trials, Scopus and Science Direct) were systematically searched in July 2017 for studies reporting non-antibiotic measures to prevent UTIs in pregnancy. The terms ("urinary tract infection" or UTI or bacteriuria or cystitis) AND (prevention) AND (pregnan*) were used. The quality of the publications was appraised using the Critical Appraisal Skills Programme (CASP) checklists for cohort study, case-control study and randomised controlled trial. The results were synthesised using a textual narrative approach.
resultsSearch results yielded 3276 publications and after reviewing titles and removing duplicates, 57 full text articles were assessed for eligibility and eight were included in the review. Five different approaches (hygiene measures, cranberry juice, immunisation, ascorbic acid and Canephron® N) have been identified, all of which are reported to be safe in pregnancy.
conclusionThe quality of the evidence varied considerably and only hygiene measures were supported by evidence to be recommended in practice. Future work needs to concentrate on strengthening the evidence base through improved design and reporting of studies with a focus on immunisation, ascorbic acid and Canephron® N.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.