Trial reportClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2018
The efficacy of transcranial random noise stimulation (tRNS) on mood may depend on individual differences including age and trait mood.
Trial report in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- What Works to Improve Wellbeing? A Rapid Systematic Review of 223 Interventions Evaluated with the Warwick-Edinburgh Mental Well-Being Scales.International journal of environmental research and public health · 2022Pooled it
- Reducing attention bias toward negative emotional stimuli with transcranial random noise stimulation: a randomized, double-blind, sham-controlled, crossover study.Scientific reports · 2025Trial
- The effects of prefrontal tDCS and hf-tRNS on the processing of positive and negative emotions evoked by video clips in first- and third-person.Scientific reports · 2024Article
- Prefrontal theta-gamma transcranial alternating current stimulation improves non-declarative visuomotor learning in older adults.Scientific reports · 2024Article
- Human neuronal excitation/inhibition balance explains and predicts neurostimulation induced learning benefits.PLoS biology · 2023Article
- New Horizons on Non-invasive Brain Stimulation of the Social and Affective Cerebellum.Cerebellum (London, England) · 2022Review
- Different stages of emotional prosody processing in healthy ageing-evidence from behavioural responses, ERPs, tDCS, and tRNS.PloS one · 2022Article
- Non-invasive brain stimulation and neuroenhancement.Clinical neurophysiology practice · 2022Review
- The Effect of Transcranial Random Noise Stimulation on Cognitive Training Outcome in Healthy Aging.Frontiers in neurology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
objectivesTo assess whether changes in brain microstructures associated with ageing and presence of cardiovascular risk factors (CVRF) reduce the efficacy of transcranial electrical stimulation (tES) improving mood in euthymic older adults.
methodsUsing excitatory high-frequency transcranial random noise stimulation (tRNS) over bilateral dorsolateral prefrontal cortex, the effect on mood was assessed in euthymic young adults (YA), older adults (HOA) and older adults with CVRF (OVR). Active-tRNS or sham was applied over two sessions. Positive and Negative Affect Schedule and Warwick Edinburgh Mental Well-being Scale measured self-reported state mood before and after stimulation. Trait mood was also measured using the Geriatric Depression Scale.
resultsResponse to tRNS seemed dependent on individual differences in age and trait mood. In HOA, more negative trait mood was associated with more positive mood change after tRNS. OVR showed a similar but reduced pattern of mood change to HOA. In YA, more positive trait mood was associated with greater positive mood change after tRNS.
conclusionsAge and trait mood may be important factors when examining the efficacy of tES as an alternative treatment for depression. SIGNIFICANCE: Future studies should consider how response to tES is affected by individual differences.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.