Evidence map›Paper›PMID 29653079›Full record

ArticleArchives of biochemistry and biophysics2018

Dominant and sensitive control of oxidative flux by the ATP-ADP carrier in human skeletal muscle mitochondria: Effect of lysine acetylation.

W T Willis, D Miranda-Grandjean, J Hudgens, E A Willis, J Finlayson, E A De Filippis, R Zapata Bustos, P R Langlais, C Mielke, L J Mandarino

Open access · bronzeAbstract read
In one paragraph

Article in Archives of biochemistry and biophysics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Oxidative phosphorylation KBiochimica et biophysica acta. Bioenergetics · 2021
    Article
  8. Human microsporidian pathogenJournal of cell science · 2021
    Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

W T WillisUniversity of Arizona, College of Medicine, Department of Medicine, 1501 N. Campbell Avenue, P.O. Box 245099, Tucson, AZ 85724-5099, USA. Electronic address: waynewillis@deptofmed.arizona.edu.
D Miranda-GrandjeanMayo Clinic, Division of Endocrinology, East Shea Boulevard and 134th Street, Scottsdale, AZ 85259, USA. Electronic address: Miranda.Danielle@mayo.edu.
J HudgensMayo Clinic, Division of Endocrinology, East Shea Boulevard and 134th Street, Scottsdale, AZ 85259, USA. Electronic address: jhudgens89@gmail.com.
E A WillisMayo Clinic, Division of Endocrinology, East Shea Boulevard and 134th Street, Scottsdale, AZ 85259, USA. Electronic address: e.willis@uky.edu.
J FinlaysonUniversity of Arizona, College of Medicine, Department of Medicine, 1501 N. Campbell Avenue, P.O. Box 245099, Tucson, AZ 85724-5099, USA. Electronic address: jfinlayson@deptofmed.arizona.edu.
E A De FilippisMayo Clinic, Division of Endocrinology, East Shea Boulevard and 134th Street, Scottsdale, AZ 85259, USA. Electronic address: DeFilippis.Elena@mayo.edu.
R Zapata BustosUniversity of Arizona, College of Medicine, Department of Medicine, 1501 N. Campbell Avenue, P.O. Box 245099, Tucson, AZ 85724-5099, USA. Electronic address: rocioz@deptofmed.arizona.edu.
P R LanglaisUniversity of Arizona, College of Medicine, Department of Medicine, 1501 N. Campbell Avenue, P.O. Box 245099, Tucson, AZ 85724-5099, USA. Electronic address: langlais@deptofmed.arizona.edu.
C MielkeMayo Clinic, Division of Endocrinology, East Shea Boulevard and 134th Street, Scottsdale, AZ 85259, USA. Electronic address: clinton.mielke@gmail.com.
L J MandarinoUniversity of Arizona, College of Medicine, Department of Medicine, 1501 N. Campbell Avenue, P.O. Box 245099, Tucson, AZ 85724-5099, USA. Electronic address: mandarino@deptofmed.arizona.edu.
Mayo Clinic in Arizona · USUniversity of Arizona · US

Funding

ZESTRIL VS. VERAPAMIL IN THE TREATMENT OF HYPERTENSIONM01RR000585 · NCRR · MAYO CLINIC ROCHESTER · PI RIZZA, ROBERT A. · 1985 to 2006
$30.4M
Institutional Career Development CoreKL2TR002379 · NCATS · MAYO CLINIC ROCHESTER · PI NILUFER ERTEKIN-TANER · 2017 to 2026
$14.9M
MOLECULAR REGULATION OF MUSCLE GLUCOSE METABOLISM IN MANR01DK047936 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR SAN ANT · PI MANDARINO, LAWRENCE J · 1994 to 2022
$10.7M
PGC-1 & Muscle Mitochondrial Dysfunction in DiabetesR01DK066483 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR SAN ANT · PI MANDARINO, LAWRENCE J · 2004 to 2018
$6.7M
NCATS NIH HHS KL2 TR002379NCRR NIH HHS M01 RR000585NIDDK NIH HHS R01 DK047936NIDDK NIH HHS R01 DK066483
6 · The paper itself

Abstract

The adenine nucleotide translocase (ANT) of the mitochondrial inner membrane exchanges ADP for ATP. Mitochondria were isolated from human vastus lateralis muscle (n = 9). Carboxyatractyloside titration of O

Indexed as

Energy MetabolismAcetylationAdenine Nucleotide Translocator 1Adenosine DiphosphateAdenosine TriphosphateAdultFemaleHumansLysineMaleMitochondria, MuscleMuscle, SkeletalOxidative PhosphorylationOxygen ConsumptionAdenine Nucleotide Translocator 1Adenosine DiphosphateAdenosine TriphosphateLysineAcetylationBioenergeticsEnergy metabolismFlux control

Identifiers

PMID29653079
PMCPMC6919326
OpenAlexW2796968842

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.