Evidence map›Paper›PMID 29653061›Full record

ArticleJournal of computational biology : a journal of computational molecular cell biology2018

To t-Test or Not to t-Test? A p-Values-Based Point of View in the Receiver Operating Characteristic Curve Framework.

Albert Vexler, Jihnhee Yu

Abstract read
In one paragraph

Article in Journal of computational biology : a journal of computational molecular cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Testing exchangeability of multivariate distributions.Journal of applied statistics · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Albert VexlerDepartment of Biostatistics, The State University of New York , Buffalo, New York.
Jihnhee YuDepartment of Biostatistics, The State University of New York , Buffalo, New York.

Funding

Modern Empirical Likelihood Methods in Biomedicine and HealthG13LM012241 · NLM · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI VEXLER, ALBERT, YU, JIHNHEE · 2016 to 2017
$100k
NLM NIH HHS G13 LM012241
6 · The paper itself

Abstract

A common statistical doctrine supported by many introductory courses and textbooks is that t-test type procedures based on normally distributed data points are anticipated to provide a standard in decision-making. In order to motivate scholars to examine this convention, we introduce a simple approach based on graphical tools of receiver operating characteristic (ROC) curve analysis, a well-established biostatistical methodology. In this context, we propose employing a p-values-based method, taking into account the stochastic nature of p-values. We focus on the modern statistical literature to address the expected p-value (EPV) as a measure of the performance of decision-making rules. During the course of our study, we extend the EPV concept to be considered in terms of the ROC curve technique. This provides expressive evaluations and visualizations of a wide spectrum of testing mechanisms' properties. We show that the conventional power characterization of tests is a partial aspect of the presented EPV/ROC technique. We desire that this explanation of the EPV/ROC approach convinces researchers of the usefulness of the EPV/ROC approach for depicting different characteristics of decision-making procedures, in light of the growing interest regarding correct p-values-based applications.

Indexed as

Area Under CurveData Interpretation, StatisticalAdultAgedBiomarkersBiostatisticsCase-Control StudiesCholesterol, HDLDiagnostic Tests, RoutineHumansMiddle AgedMyocardial InfarctionBiomarkersCholesterol, HDLAUCexpected p-valuepartial AUCpartial expected p-valuepowerp-valueROC curvet-testWilcoxon test

Identifiers

PMID29653061
PMCPMC5998834

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.