Evidence map›Paper›PMID 29652825›Full record

ArticleNanomaterials (Basel, Switzerland)2018

Fabrication of Sericin/Agrose Gel Loaded Lysozyme and Its Potential in Wound Dressing Application.

Meirong Yang, Yejing Wang, Gang Tao, Rui Cai, Peng Wang, Liying Liu, Lisha Ai, Hua Zuo, Ping Zhao, Ahmad Umar and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 50 citations in OpenAlex.

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  7. Heliyon · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Meirong YangState Key Laboratory of Silkworm Genome Biology, Southwest University, Beibei, Chongqing 400715, China. yangmeirong@email.swu.edu.cn.
Yejing WangState Key Laboratory of Silkworm Genome Biology, Southwest University, Beibei, Chongqing 400715, China. yjwang@swu.edu.cn.
Gang TaoState Key Laboratory of Silkworm Genome Biology, Southwest University, Beibei, Chongqing 400715, China. taogang@email.swu.edu.cn.
Rui CaiCollege of Biotechnology, Southwest University, Beibei, Chongqing 400715, China. cairui0330@email.swu.edu.cn.
Peng WangCollege of Biotechnology, Southwest University, Beibei, Chongqing 400715, China. modelsums@email.swu.edu.cn.
Liying LiuState Key Laboratory of Silkworm Genome Biology, Southwest University, Beibei, Chongqing 400715, China. l3341345@email.swu.edu.cn.
Lisha AiState Key Laboratory of Silkworm Genome Biology, Southwest University, Beibei, Chongqing 400715, China. als123@email.swu.edu.cn.
Hua ZuoCollege of Pharmaceutical Sciences, Southwest University, Beibei, Chongqing 400715, China. zuohua@swu.edu.cn.
Ping ZhaoState Key Laboratory of Silkworm Genome Biology, Southwest University, Beibei, Chongqing 400715, China. zhaop@swu.edu.cn.
Ahmad UmarDepartment of Chemistry, College of Science and Arts and Promising Centre for Sensors and Electronics Devices (PCSED), Najran University, P.O. Box 1988, Najran 11001, Saudi Arabia. umahmad@nu.edu.sa.
Chuanbin MaoDepartment of Chemistry & Biochemistry, Stephenson Life Science Research Center, University of Oklahoma, 101 Stephenson Parkway, Norman, OK 73019, USA. cbmao@ou.edu.
Huawei HeState Key Laboratory of Silkworm Genome Biology, Southwest University, Beibei, Chongqing 400715, China. hehuawei@swu.edu.cn.ORCID 0000-0002-3805-8940
Southwest University · CNNajran University · SAStephens College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sericin is a biomaterial resource for its significant biodegradability, biocompatibility, hydrophilicity, and reactivity. Designing a material with superabsorbent, antiseptic, and non-cytotoxic wound dressing properties is advantageous to reduce wound infection and promote wound healing. Herein, we propose an environment-friendly strategy to obtain an interpenetrating polymer network gel through blending sericin and agarose and freeze-drying. The physicochemical characterizations of the sericin/agarose gel including morphology, porosity, swelling behavior, crystallinity, secondary structure, and thermal property were well characterized. Subsequently, the lysozyme loaded sericin/agarose composite gel was successfully prepared by the solution impregnation method. To evaluate the potential of the lysozyme loaded sericin/agarose gel in wound dressing application, we analyzed the lysozyme loading and release, antimicrobial activity, and cytocompatibility of the resulting gel. The results showed the lysozyme loaded composite gel had high porosity, excellent water absorption property, and good antimicrobial activities against

Indexed as

agarosecomposite gellysozymesilk sericinwound dressing

Identifiers

PMID29652825
PMCPMC5923565
OpenAlexW2796827469

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.