Trial reportSpine2018
Long-Term Results of Surgery Compared With Nonoperative Treatment for Lumbar Degenerative Spondylolisthesis in the Spine Patient Outcomes Research Trial (SPORT).
Trial report in Spine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Emerging innovations for lumbar spondylolisthesis management: a systematic review of active and prospective clinical trials.Neurosurgical review · 2022Pooled it
- Is Biportal Endoscopic Spine Surgery More Advantageous Than Uniportal for the Treatment of Lumbar Degenerative Disease? A Meta-Analysis.Medicina (Kaunas, Lithuania) · 2022Pooled it
- Non-operative treatment for lumbar spinal stenosis with neurogenic claudication: an updated systematic review.BMJ open · 2022Pooled it
- Hip Arthroscopy Versus Physical Therapy for the Treatment of Symptomatic Acetabular Labral Tears in Patients Older Than 40 Years: 24-Month Results From a Randomized Controlled Trial.The American journal of sports medicine · 2024Trial
- Long-term (> 10 years) clinical outcomes of instrumented posterolateral fusion for spondylolisthesis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021Trial
- Epidural Steroid Injections for Management of Degenerative Spondylolisthesis: Little Effect on Clinical Outcomes in Operatively and Nonoperatively Treated Patients.The Journal of bone and joint surgery. American volume · 2020Trial
- Improvement in physical and mental quality of life following reduction of lumbar spondylolisthesis using chiropractic BioPhysicsEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Absence of bone marrow edema on early postoperative MRI predicts fusion outcome after single-level lumbar interbody fusion.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Comparison of biportal versus uniportal endoscopic decompression for the treatment of lumbar degenerative disease: a systematic review and meta‑analysis.Asian spine journal · 2026Review
- Cost and Utilization Trends of Lumbar Fusion.JAMA network open · 2026Article
- Intervertebral disc degeneration.Nature reviews. Disease primers · 2026Review
- The long-term clinical course of non-surgically treated lumbar spinal stenosis: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Review
- Review
- Multifidus degeneration correlates with the extent of L4 translation in degenerative lumbar spondylolisthesis.Brain & spine · 2026Article
- Unilateral biportal endoscopic decompression for two-level adjacent lumbar spinal stenosis through a single sliding approach: technical report and early follow-up.Journal of orthopaedic surgery and research · 2025Article
- Review
- Advancements in biomaterials and bioactive solutions for lumbar spine fusion cages: Current trends and future perspectives.Bioactive materials · 2025Review
- Biportal endoscopic versus conventional open spine surgery for lumbar degenerative disease: a systematic review and meta‑analysis.Asian spine journal · 2025Article
- Comparing fusion and complication rates after instrumented versus uninstrumented fusion for lumbar spondylolisthesis: A systematic review and meta analysis of randomized controlled trials with trial sequential analysis.Journal of orthopaedics · 2025Review
- Artificial intelligence and machine learning in spine care: Advancing precision diagnosis, treatment, and rehabilitation.World journal of orthopedics · 2025Review
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
STUDY
designRandomized trial with a concurrent observational cohort study.
objectiveTo compare 8-year outcomes between surgery and nonoperative care and among different fusion techniques for symptomatic lumbar degenerative spondylolisthesis (DS). SUMMARY OF BACKGROUND DATA: Surgical treatment of DS has been shown to be more effective than nonoperative treatment out to 4 years. This study sought to further determine the long-term (8-year) outcomes.
methodsSurgical candidates with DS from 13 centers with at least 12 weeks of symptoms and confirmatory imaging were offered enrollment in a randomized controlled trial (RCT) or observational cohort study (OBS). Treatment consisted of standard decompressive laminectomy (with or without fusion) versus standard nonoperative care. Primary outcome measures were the Short Form-36 (SF-36) bodily pain and physical function scores and the modified Oswestry Disability Index at 6 weeks, 3 months, 6 months, and yearly up to 8 years.
resultsData were obtained for 69% of the randomized cohort and 57% of the observational cohort at the 8-year follow up. Intent-to-treat analyses of the randomized group were limited by high levels of nonadherence to the randomized treatment. As-treated analyses in the randomized and observational groups showed significantly greater improvement in the surgery group on all primary outcome measures at all time points through 8 years. Outcomes were similar among patients treated with uninstrumented posterolateral fusion, instrumented posterolateral fusion, and 360° fusion.
conclusionFor patients with symptomatic DS, patients who received surgery had significantly greater improvements in pain and function compared with nonoperative treatment through 8 years of follow-up. Fusion technique did not affect outcomes. LEVEL OF EVIDENCE: 1.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.