Evidence map›Paper›PMID 29652633›Full record

ReviewPhysiological genomics2018

Glucose, insulin, and the carotid body chemoreceptors in humans.

Jacqueline K Limberg

Abstract readReview
In one paragraph

Review in Physiological genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Role of the carotid chemoreceptors in insulin-mediated sympathoexcitation in humans.American journal of physiology. Regulatory, integrative and comparative physiology · 2020
    Trial
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Jacqueline K LimbergDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota and Department of Nutrition and Exercise Physiology, University of Missouri , Columbia, Missouri.

Funding

MECHANISMS OF INSULIN RESISTANCE IN MANR01DK029953 · NIDDK · UNIVERSITY OF VIRGINIA · PI BASU, RITA · 1986 to 2024
$11.5M
DIABETES AND METABOLISMT32DK007352 · NIDDK · MAYO CLINIC ROCHESTER · PI MICHAEL D. JENSEN · 1986 to 2026
$9.4M
Role of Carotid Bodies in Glucose Regulation and Counter Regulation in HumansR01DK090541 · NIDDK · MAYO CLINIC ROCHESTER · PI BASU, RITA · 2011 to 2014
$2.6M
Reflex responses to intermittent hypoxia in humans: Mechanisms and consequencesR00HL130339 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI LIMBERG, JACQUELINE K · 2017 to 2019
$729k
Reflex responses to intermittent hypoxia in humans: Mechanisms and consequencesK99HL130339 · NHLBI · MAYO CLINIC ROCHESTER · PI LIMBERG, JACQUELINE K · 2016 to 2017
$156k
Insulin-sensing capabilities of the carotid chemoreceptorsF32HL120570 · NHLBI · MAYO CLINIC ROCHESTER · PI LIMBERG, JACQUELINE K · 2014 to 2015
$67k
NHLBI NIH HHS F32 HL120570NHLBI NIH HHS K99 HL130339NHLBI NIH HHS R00 HL130339NIDDK NIH HHS R01 DK029953NIDDK NIH HHS R01 DK090541NIDDK NIH HHS T32 DK007352
6 · The paper itself

Abstract

Known primarily for its oxygen-sensing capabilities, the carotid body chemoreceptors have recently been implicated, primarily by work in animal models, in the pathophysiology of a number of metabolic conditions. The research presented in this brief review highlights translational work conducted at the Mayo Clinic between 2010 and 2017 in healthy humans and discusses key areas for future work in disease populations.

Indexed as

AnimalsCarotid BodyChemoreceptor CellsGlucoseHumansHypoxiaInsulinOxygenTranslational Research, BiomedicalGlucoseInsulinOxygencarotid bodychemoreflexhumanshypoxic ventilatory response

Identifiers

PMID29652633
PMCPMC6087880

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.