Evidence map›Paper›PMID 29652397›Full record

ArticleOptics letters2018

Three-photon fluorescence microscopy with an axially elongated Bessel focus.

Cristina Rodríguez, Yajie Liang, Rongwen Lu, Na Ji

Abstract read
In one paragraph

Article in Optics letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Measuring capillary flow dynamics using interlaced two-photon volumetric scanning.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. GraFT: Graph Filtered Temporal Dictionary Learning for Functional Neural Imaging.IEEE transactions on image processing : a publication of the IEEE Signal Processing Society · 2022
    Article
  15. Review
  16. Article
  17. Optica · 2021
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cristina Rodríguez
Yajie Liang
Rongwen Lu
Na Ji

Funding

High-Speed Volumetric Imaging of Neural Activity throughout the Living Brain - Supplement RequestU01NS103489 · NINDS · UNIVERSITY OF CALIFORNIA BERKELEY · PI JI, NA · 2017 to 2019
$2.7M
Calcium biosensors for deep-tissue imaging and spectral multiplexingU01NS103573 · NINDS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI VERKHUSHA, VLADISLAV · 2017 to 2019
$1.8M
Large-scale analysis of functional synapses during circuit plasticity with novel optogenetic sensorsU01NS103571 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI TIAN, LIN, ZITO, KAREN · 2017 to 2019
$1.7M
Howard Hughes Medical InstituteNINDS NIH HHS U01 NS103489NINDS NIH HHS U01 NS103571NINDS NIH HHS U01 NS103573
6 · The paper itself

Abstract

Volumetric imaging tools that are simple to adopt, flexible, and robust are in high demand in the field of neuroscience, where the ability to image neurons and their networks with high spatiotemporal resolution is essential. Using an axially elongated focus approximating a Bessel beam, in combination with two-photon fluorescence microscopy, has proven successful at such an endeavor. Here, we demonstrate three-photon fluorescence imaging with an axially extended Bessel focus. We use an axicon-based module that allowed for the generation of Bessel foci of varying numerical apertures and axial lengths, and apply this volumetric imaging tool to image mouse brain slices and for in vivo imaging of the mouse brain.

Indexed as

LightMicroscopy, Fluorescence, MultiphotonAnimalsBrainComputer SimulationElectromagnetic RadiationEquipment DesignFourier AnalysisImage Processing, Computer-AssistedImaging, Three-DimensionalMiceMicromanipulationMicroscopy

Identifiers

PMID29652397
PMCPMC5986555

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.