ArticleeLife2018
Motor selection dynamics in FEF explain the reaction time variance of saccades to single targets.
Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Frontal Eye Field Leads a Distributed Oculomotor Circuit for Abstract Categorical Decisions.bioRxiv : the preprint server for biology · 2026Article
- Much higher covariation with foveation timing by superior colliculus than primary visual cortical neuronal activity.iScience · 2026Article
- Enhanced reward coding and condition-independent dynamics in optogenetically identified corticostriatal neurons in monkeys.Nature communications · 2026Article
- Working Memory of Multi-Object Scenes in Primate Frontal Cortex.bioRxiv : the preprint server for biology · 2026Article
- Pupil size predicts exploration through critical slowing in prefrontal dynamics.Communications biology · 2025Article
- Pupil size predicts the onset of exploration and changes in prefrontal dynamics.bioRxiv : the preprint server for biology · 2025Article
- Article
- Location- and feature-based selection histories make independent, qualitatively distinct contributions to urgent visuomotor performance.bioRxiv : the preprint server for biology · 2025Article
- Human response times are governed by dual anticipatory processes with distinct neural signatures.Communications biology · 2025Article
- Conditional independence as a statistical assessment of evidence integration processes.PloS one · 2024Article
- The representation of priors and decisions in the human parietal cortex.PLoS biology · 2024Article
- Conditional independence as a statistical assessment of evidence integration processes.bioRxiv : the preprint server for biology · 2023Article
- Generalised exponential-Gaussian distribution: a method for neural reaction time analysis.Cognitive neurodynamics · 2023Article
- Salience by competitive and recurrent interactions: Bridging neural spiking and computation in visual attention.Psychological review · 2022Article
- Population temporal structure supplements the rate code during sensorimotor transformations.Current biology : CB · 2022Article
- Under time pressure, the exogenous modulation of saccade plans is ubiquitous, intricate, and lawful.Current opinion in neurobiology · 2021Review
- The unknown but knowable relationship between Presaccadic Accumulation of activity and Saccade initiation.Journal of computational neuroscience · 2021Article
- Neural Substrates of the Drift-Diffusion Model in Brain Disorders.Frontiers in computational neuroscience · 2021Review
- Article
- The Neural Basis for Response Latency in a Sensory-Motor Behavior.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
In studies of voluntary movement, a most elemental quantity is the reaction time (RT) between the onset of a visual stimulus and a saccade toward it. However, this RT demonstrates extremely high variability which, in spite of extensive research, remains unexplained. It is well established that, when a visual target appears, oculomotor activity gradually builds up until a critical level is reached, at which point a saccade is triggered. Here, based on computational work and single-neuron recordings from monkey frontal eye field (FEF), we show that this rise-to-threshold process starts from a dynamic initial state that already contains other incipient, internally driven motor plans, which compete with the target-driven activity to varying degrees. The ensuing conflict resolution process, which manifests in subtle covariations between baseline activity, build-up rate, and threshold, consists of fundamentally deterministic interactions, and explains the observed RT distributions while invoking only a small amount of intrinsic randomness.
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Registered trials
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