ReviewAccounts of chemical research2018
Optical Probes for Neurobiological Sensing and Imaging.
Review in Accounts of chemical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 62 citations in OpenAlex.
- A modular, adaptable, and accessible implant kit for chronic electrophysiological recordings in rats.Cell reports methods · 2025Article
- Biological and Mechanical Limitations for Chronic Fast-Scan Cyclic Voltammetry Sensor Design.Advanced materials technologies · 2025Article
- Nanomaterial-Based Sensing Systems to Detect Neuropharmaceutical Compounds and Neurotransmitters.Sensors (Basel, Switzerland) · 2025Review
- The Programmable Catalytic Core of 8-17 DNAzymes.Molecules (Basel, Switzerland) · 2024Article
- Combining nitric oxide and calcium sensing for the detection of endothelial dysfunction.Communications chemistry · 2023Review
- Spatiotemporal Imaging of Zinc Ions in Zebrafish Live Brain Tissue Enabled by Fluorescent Bionanoprobes.Molecules (Basel, Switzerland) · 2023Article
- Novel Fluorescence Probe toward CuBiosensors · 2022Article
- Neuron devices: emerging prospects in neural interfaces and recognition.Microsystems & nanoengineering · 2022Review
- Imaging and Quantification of Intact Neuronal Dendrites via CLARITY Tissue Clearing.Journal of visualized experiments : JoVE · 2021Article
- Fluorescence-Based Sensing of Pesticides Using Supramolecular Chemistry.Frontiers in chemistry · 2021Review
- Expanding the Genetic Code for Neuronal Studies.Chembiochem : a European journal of chemical biology · 2020Review
- Application of Nanomaterials in Biomedical Imaging and Cancer Therapy.Nanomaterials (Basel, Switzerland) · 2020Review
- Molecular Fluorophores for Deep-Tissue Bioimaging.ACS central science · 2020Review
- Article
- A sensitive and specific nanosensor for monitoring extracellular potassium levels in the brain.Nature nanotechnology · 2020Article
- A highly sensitive and selective nanosensor for near-infrared potassium imaging.Science advances · 2020Article
- Biosensors for Studies on Adhesion-Mediated Cellular Responses to Their Microenvironment.Frontiers in bioengineering and biotechnology · 2020Review
- MoSScience advances · 2019Article
- Neurotransmitter-Responsive Nanosensors forJournal of the American Chemical Society · 2019Article
- Next-generation interfaces for studying neural function.Nature biotechnology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Fluorescent nanosensors and molecular probes are next-generation tools for imaging chemical signaling inside and between cells. Electrophysiology has long been considered the gold standard in elucidating neural dynamics with high temporal resolution and precision, particularly on the single-cell level. However, electrode-based techniques face challenges in illuminating the specific chemicals involved in neural cell activation with adequate spatial information. Measuring chemical dynamics is of fundamental importance to better understand synergistic interactions between neurons as well as interactions between neurons and non-neuronal cells. Over the past decade, significant technological advances in optical probes and imaging methods have enabled entirely new possibilities for studying neural cells and circuits at the chemical level. These optical imaging modalities have shown promise for combining chemical, temporal, and spatial information. This potential makes them ideal candidates to unravel the complex neural interactions at multiple scales in the brain, which could be complemented by traditional electrophysiological methods to obtain a full spatiotemporal picture of neurochemical dynamics. Despite the potential, only a handful of probe candidates have been utilized to provide detailed chemical information in the brain. To date, most live imaging and chemical mapping studies rely on fluorescent molecular indicators to report intracellular calcium (Ca
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.