Evidence map›Paper›PMID 29651892›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2019

The intracerebral hemorrhage blood transcriptome in humans differs from the ischemic stroke and vascular risk factor control blood transcriptomes.

Boryana Stamova, Bradley P Ander, Glen Jickling, Farah Hamade, Marc Durocher, Xinhua Zhan, Da Zhi Liu, Xiyuan Cheng, Heather Hull, Alan Yee and 3 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 76 citations in OpenAlex.

  1. Trial
  2. Molecular heterogeneity in human stroke - What can we learn from the peripheral blood transcriptome?Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Review
  3. Article
  4. NFAT1Cellular & molecular biology letters · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. CNS-peripheral immune interactions in hemorrhagic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Review
  18. Long non-coding RNAs in intracerebral hemorrhage.Frontiers in molecular neuroscience · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 2 countries.

Boryana Stamova1 Department of Neurology, School of Medicine, University of California at Davis, Sacramento, CA, USA.
Bradley P Ander1 Department of Neurology, School of Medicine, University of California at Davis, Sacramento, CA, USA.
Glen Jickling1 Department of Neurology, School of Medicine, University of California at Davis, Sacramento, CA, USA.
Farah Hamade1 Department of Neurology, School of Medicine, University of California at Davis, Sacramento, CA, USA.
Marc Durocher1 Department of Neurology, School of Medicine, University of California at Davis, Sacramento, CA, USA.
Xinhua Zhan1 Department of Neurology, School of Medicine, University of California at Davis, Sacramento, CA, USA.
Da Zhi Liu1 Department of Neurology, School of Medicine, University of California at Davis, Sacramento, CA, USA.
Xiyuan Cheng1 Department of Neurology, School of Medicine, University of California at Davis, Sacramento, CA, USA.
Heather Hull1 Department of Neurology, School of Medicine, University of California at Davis, Sacramento, CA, USA.
Alan Yee1 Department of Neurology, School of Medicine, University of California at Davis, Sacramento, CA, USA.
Kwan Ng1 Department of Neurology, School of Medicine, University of California at Davis, Sacramento, CA, USA.
Natasha Shroff1 Department of Neurology, School of Medicine, University of California at Davis, Sacramento, CA, USA.
Frank R Sharp1 Department of Neurology, School of Medicine, University of California at Davis, Sacramento, CA, USA.
University of California, Davis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding how the blood transcriptome of human intracerebral hemorrhage (ICH) differs from ischemic stroke (IS) and matched controls (CTRL) will improve understanding of immune and coagulation pathways in both disorders. This study examined RNA from 99 human whole-blood samples using GeneChip® HTA 2.0 arrays to assess differentially expressed transcripts of alternatively spliced genes between ICH, IS and CTRL. We used a mixed regression model with FDR-corrected

Indexed as

TranscriptomeAgedAlternative SplicingBrain IschemiaCerebral HemorrhageFemaleHumansMaleMiddle AgedStrokeAlternative splicingangiogenesisintracerebral hemorrhageischemic strokeT-cell receptors

Identifiers

PMID29651892
PMCPMC6727143
OpenAlexW2798052076

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.