Evidence map›Paper›PMID 29651824›Full record

ArticleJournal of biomedical optics2018

Effect of optical aberrations on intraocular pressure measurements using a microscale optical implant in ex vivo rabbit eyes.

Samuel J Han, Haeri Park, Jeong Oen Lee, Hyuck Choo

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Samuel J HanCalifornia Institute of Technology, Department of Medical Engineering, Pasadena, California, United States.
Haeri ParkCalifornia Institute of Technology, Department of Medical Engineering, Pasadena, California, United States.
Jeong Oen LeeCalifornia Institute of Technology, Department of Medical Engineering, Pasadena, California, United States.
Hyuck ChooCalifornia Institute of Technology, Department of Medical Engineering, Pasadena, California, United States.

Funding

Intraocular Pressure Sensing Using LightR01EY024582 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHOO, HYUCK, SRETAVAN, DAVID W · 2016 to 2018
$989k
NEI NIH HHS R01 EY024582
6 · The paper itself

Abstract

Elevated intraocular pressure (IOP) is the only modifiable major risk factor of glaucoma. Recently, accurate and continuous IOP monitoring has been demonstrated in vivo using an implantable sensor based on optical resonance with remote optical readout to improve patient outcomes. Here, we investigate the relationship between optical aberrations of ex vivo rabbit eyes and the performance of the IOP sensor using a custom-built setup integrated with a Shack-Hartmann sensor. The sensor readouts became less accurate as the aberrations increased in magnitude, but they remained within the clinically acceptable range. For root-mean-square wavefront errors of 0.10 to 0.94  μm, the accuracy and the signal-to-noise ratio were 0.58  ±  0.32  mm Hg and 15.57  ±  4.85  dB, respectively.

Indexed as

AnimalsEquipment DesignEyeGlaucomaIntraocular PressureMonitoring, PhysiologicOptical ImagingProstheses and ImplantsRabbitsSignal-To-Noise Ratioaberrationglaucomalightmedical devicesoptics

Identifiers

PMID29651824
PMCPMC8357320

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.