Evidence map›Paper›PMID 29651678›Full record

ArticleJournal of general internal medicine2018

Performance of the 2015 US Preventive Services Task Force Screening Criteria for Prediabetes and Undiagnosed Diabetes.

Matthew J O'Brien, Kai McKeever Bullard, Yan Zhang, Edward W Gregg, Mercedes R Carnethon, Namratha R Kandula, Ronald T Ackermann

Open access · bronzeAbstract read
In one paragraph

Article in Journal of general internal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Increasing Diabetes Screening in a Primary Care Setting.Clinical diabetes : a publication of the American Diabetes Association · 2022
    Article
  5. Screening for Diabetes and Prediabetes.Endocrinology and metabolism clinics of North America · 2021
    Review
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Matthew J O'BrienDivision of General Internal Medicine and Geriatrics, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. matthew.obrien1@northwestern.edu.
Kai McKeever BullardDivision of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Yan ZhangDivision of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Edward W GreggDivision of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Mercedes R CarnethonDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Namratha R KandulaDivision of General Internal Medicine and Geriatrics, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Ronald T AckermannDivision of General Internal Medicine and Geriatrics, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Northwestern University · USCenters for Disease Control and Prevention · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Research Design, Data, and Analytics CoreP30DK092949 · NIDDK · UNIVERSITY OF CHICAGO · PI Ronald T. Ackermann, MARSHALL H CHIN · 2011 to 2026
$10.0M
Mediators of Atherosclerosis in South Asians Living in AmericaR01HL093009 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KANAYA, ALKA M. · 2010 to 2018
$5.4M
Improving Diabetes Risk Assessment and Screening in Minority-Predominant Community Health Center PatientsR21DK112066 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI O'BRIEN, MATTHEW JAMES · 2016 to 2017
$429k
NCATS NIH HHS UL1 TR001422NHLBI NIH HHS R01 HL093009NIDDK NIH HHS P30 DK092949NIDDK NIH HHS R21 DK112066
6 · The paper itself

Abstract

backgroundIn 2015, The US Preventive Services Task Force (USPSTF) recommended screening for prediabetes and undiagnosed diabetes (collectively called dysglycemia) among adults aged 40-70 years with overweight or obesity. The recommendation suggests that clinicians consider screening earlier in people who have other diabetes risk factors.

objectiveTo compare the performance of limited and expanded screening criteria recommended by the USPSTF for detecting dysglycemia among US adults.

designCross-sectional analysis of survey and laboratory data collected from nationally representative samples of the civilian, noninstitutionalized US adult population.

participantsA total of 3643 adults without diagnosed diabetes who underwent measurement of hemoglobin A1c (A1c), fasting plasma glucose (FPG), and 2-h plasma glucose (2-h PG). MAIN MEASURES: Screening eligibility according to the limited criteria was based on age 40 to 70 years old and overweight/obesity. Screening eligibility according to the expanded criteria was determined by meeting the limited criteria or having ≥ 1 of the following risk factors: family history of diabetes, history of gestational diabetes or polycystic ovarian syndrome, and non-white race/ethnicity. Dysglycemia was defined by A1c ≥ 5.7%, FPG ≥ 100 mg/dL, and/or 2-h PG ≥ 140 mg/dL. KEY

resultsAmong the US adult population without diagnosed diabetes, 49.7% had dysglycemia. Screening based on the limited criteria demonstrated a sensitivity of 47.3% (95% CI, 44.7-50.0%) and specificity of 71.4% (95% CI, 67.3-75.2%). The expanded criteria yielded higher sensitivity [76.8% (95% CI, 73.5-79.8%)] and lower specificity [33.8% (95% CI, 30.1-37.7%)]. Point estimates for the sensitivity of the limited criteria were lower in all minority groups and significantly different for Asians compared to non-Hispanic whites [29.9% (95% CI, 23.4-37.2%) vs. 49.8% (95% CI, 45.9-53.7%); P < .001].

conclusionsDiabetes screening that follows the limited USPSTF criteria will identify approximately half of US adults with dysglycemia. Screening other high-risk subgroups defined in the USPSTF recommendation would improve detection of dysglycemia and may reduce associated racial/ethnic disparities.

Indexed as

AdultAdvisory CommitteesAgedBlood GlucoseCross-Sectional StudiesFemaleHumansMaleMass ScreeningMiddle AgedNutrition SurveysPrediabetic StatePreventive Health ServicesUnited StatesBlood Glucosediabetesdiabetes screeningdysglycemiaprediabetesundiagnosed diabetes

Identifiers

PMID29651678
PMCPMC6025671
OpenAlexW2798217225

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.