Evidence map›Paper›PMID 29651586›Full record

ArticleClinical neuroradiology2019

Revascularization Techniques for Acute Basilar Artery Occlusion : Technical Considerations and Outcome in the Setting of Severe Posterior Circulation Steno-Occlusive Disease.

Eberhard Siebert, Georg Bohner, Sarah Zweynert, Volker Maus, Anastasios Mpotsaris, Thomas Liebig, Christoph Kabbasch

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Clinical neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
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  5. Management of posterior circulation tandem occlusions in acute ischemic stroke: Recanalize the dominant vertebral artery with priority.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Eberhard SiebertInstitute of Neuroradiology, Charité-University Medicine Berlin, Charitéplatz 1, 10117, Berlin, Germany. eberhard.siebert@charite.de.ORCID http://orcid.org/0000-0001-7395-6546
Georg BohnerInstitute of Neuroradiology, Charité-University Medicine Berlin, Charitéplatz 1, 10117, Berlin, Germany.
Sarah ZweynertDept. of Neurology, Charité-University Medicine Berlin, Berlin, Germany.
Volker MausDept. of Neuroradiology, University Hospital of Cologne, Cologne, Germany.
Anastasios MpotsarisDept. of Neuroradiology, University Hospital of Cologne, Cologne, Germany.
Thomas LiebigInstitute of Neuroradiology, Charité-University Medicine Berlin, Charitéplatz 1, 10117, Berlin, Germany.
Christoph KabbaschDept. of Neuroradiology, University Hospital of Cologne, Cologne, Germany.
Charité - Universitätsmedizin Berlin · DEUniversity Hospital Cologne · DEUniversitätsklinikum Aachen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe the clinical and radiological characteristics, frequency, technical aspects and outcome of endovascular treatment of acute basilar artery occlusion (ABO) in the setting of vertebrobasilar steno-occlusive disease.

methodsRetrospective analysis of databases of two universitary stroke centers including all consecutive patients from January 2013 until May 2017 undergoing thrombectomy for a) acute stroke due to basilar artery occlusion and either significant basilar artery stenosis or vertebral artery stenosis/occlusion as well as b) presumed embolic basilar artery occlusions. Demographics, stroke characteristics, time metrics, recanalization results and outcome were recorded. Interventional strategies were evaluated concerning the thrombectomy technique, additional angioplasty, type of approach with respect to lesion pattern (ipsilateral to steno-occlusive VA lesion: dirty road or contralateral: clean road) and sequence of actions.

resultsOut of 157 patients treated for ABO 38 (24.2%) had associated significant vertebrobasilar steno-occlusive lesions. An underlying significant basilar artery stenosis was present in 23.7% and additionally significant steno-occlusive vertebral lesions were present in 81.5%. Thrombectomy was performed with primary aspiration in 15.8% and with stent-retrievers in 84.2%. Successful revascularization (TICI 2b-3) was achieved in 86.8%. In 52.6% additional stent angioplasty was performed, in 7.9% balloon angioplasty only. The clean road approach was used in 22.5% of cases, the dirty road in 77.4%. Final modified Rankin scale (mRS) was 0-2 in 6 patients (15.8%) and 3-5 in 32 (84.2%). The in-hospital mortality was 36.8%. There were no statistically significant differences in outcome compared to presumed cases of embolisms.

conclusionEndovascular treatment of ABO with underlying significant vertebrobasilar steno-occlusive lesions is effective and reasonably safe. Specific procedural strategies apply depending on individual patient pathology and anatomy. Although high rates of recanalization can be achieved, outcomes tend to be poor.

Indexed as

Acute DiseaseAdultAgedAged, 80 and overCerebral RevascularizationComputed Tomography AngiographyDatabases, FactualEndovascular ProceduresFemaleHumansIschemic Attack, TransientMagnetic Resonance AngiographyMaleMiddle AgedOperative TimeRetrospective StudiesBasilar artery occlusionStrokeTandem occlusionThrombectomyVertebral artery occlusion

Identifiers

PMID29651586
OpenAlexW2798185559

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.