Evidence map›Paper›PMID 29651565›Full record

ArticleEJNMMI research2018

Synthesis and preclinical evaluation of novel

Stephanie Robu, Alexander Schmidt, Matthias Eiber, Margret Schottelius, Thomas Günther, Behrooz Hooshyar Yousefi, Markus Schwaiger, Hans-Jürgen Wester

Abstract read
In one paragraph

Article in EJNMMI research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Repeatability of QuantitativeJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2020
    Trial
  2. In vivo stableEJNMMI radiopharmacy and chemistry · 2024
    Article
  3. Review
  4. Development of the FirstPharmaceutics · 2023
    Article
  5. Comparative study ofFrontiers in medicine · 2023
    Article
  6. Article
  7. Diagnostic value of integratedProstate international · 2022
    Article
  8. Review
  9. Synthesis and Preclinical Evaluation of aJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021
    Article
  10. Article
  11. Preclinical comparison of four [EJNMMI research · 2020
    Article
  12. Article
  13. Article
  14. "Luke! Luke! Don't! It's a trap!"-spotlight on bias in animal experiments in nuclear oncology.European journal of nuclear medicine and molecular imaging · 2020
    Article
  15. Radiohybrid Ligands: A Novel Tracer Concept Exemplified byJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2020
    Article
  16. Theranostics · 2020
    Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Stephanie RobuChair of Pharmaceutical Radiochemistry, Technical University Munich, Walther-Meissner-Strasse 3, 85748, Garching, Germany. stephanie.robu@tum.de.
Alexander SchmidtChair of Pharmaceutical Radiochemistry, Technical University Munich, Walther-Meissner-Strasse 3, 85748, Garching, Germany.
Matthias EiberDepartment of Nuclear Medicine, Klinikum rechts der Isar, Technical University Munich, Ismaningerstr. 22, 81675, Munich, Germany.
Margret SchotteliusChair of Pharmaceutical Radiochemistry, Technical University Munich, Walther-Meissner-Strasse 3, 85748, Garching, Germany.
Thomas GüntherChair of Pharmaceutical Radiochemistry, Technical University Munich, Walther-Meissner-Strasse 3, 85748, Garching, Germany.
Behrooz Hooshyar YousefiDepartment of Nuclear Medicine, Klinikum rechts der Isar, Technical University Munich, Ismaningerstr. 22, 81675, Munich, Germany.
Markus SchwaigerDepartment of Nuclear Medicine, Klinikum rechts der Isar, Technical University Munich, Ismaningerstr. 22, 81675, Munich, Germany.
Hans-Jürgen WesterChair of Pharmaceutical Radiochemistry, Technical University Munich, Walther-Meissner-Strasse 3, 85748, Garching, Germany.

Funding

Deutsche Forschungsgemeinschaft SFB824, subproject B11, Z1
6 · The paper itself

Abstract

backgroundDue to its high and consistent expression in prostate cancer (PCa), the prostate-specific membrane antigen (PSMA) represents an ideal target for molecular imaging and targeted therapy using highly specific radiolabeled PSMA ligands. To address the continuously growing clinical demand for

resultsRadiolabeling procedures allowed preparation of (1) and (2) with high radiochemical yields (67 ± 7 and 53 ± 7%, d.c.) and purity (> 98%). When compared with

conclusionBoth

Indexed as

18F-DCFPyl18F-labeled EuE-based inhibitors18F-PSMA-1007PET prostate Cancer imagingPSMA

Identifiers

PMID29651565
PMCPMC5897267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.