Evidence map›Paper›PMID 29651443›Full record

ArticleJournal of immunology research2018

Immature Dendritic Cell Therapy Confers Durable Immune Modulation in an Antigen-Dependent and Antigen-Independent Manner in Nonobese Diabetic Mice.

Jeannette Lo, Chang-Qing Xia, Ruihua Peng, Michael J Clare-Salzler

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

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  10. Immunoregulatory Effect ofDrug design, development and therapy · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jeannette LoDepartment of Pathology, Immunology and Laboratory Medicine, Center for Immunology and Transplantation, University of Florida, Gainesville, FL 32610, USA.
Chang-Qing XiaDepartment of Pathology, Immunology and Laboratory Medicine, Center for Immunology and Transplantation, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0002-3832-1091
Ruihua PengDepartment of Pathology, Immunology and Laboratory Medicine, Center for Immunology and Transplantation, University of Florida, Gainesville, FL 32610, USA.
Michael J Clare-SalzlerDepartment of Pathology, Immunology and Laboratory Medicine, Center for Immunology and Transplantation, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0001-5446-559X
University of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dendritic cell (DC) immunotherapy has been effective for prevention of type 1 diabetes (T1D) in NOD mice but fails to protect if initiated after active autoimmunity. As autoreactivity expands inter- and intramolecularly during disease progression, we investigated whether DCs unpulsed or pulsed with

Indexed as

AnimalsAntigen PresentationAutoantigensAutoimmunityCell DifferentiationCell ProliferationCells, CulturedDendritic CellsDiabetes Mellitus, Type 1Disease Models, AnimalEpitopes, T-LymphocyteFemaleForkhead Transcription FactorsHumansImmune ToleranceImmunodominant EpitopesAutoantigensEpitopes, T-LymphocyteForkhead Transcription FactorsFoxp3 protein, mouseImmunodominant Epitopes

Identifiers

PMID29651443
PMCPMC5832131
OpenAlexW2788876284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.