Evidence map›Paper›PMID 29651432›Full record

ArticleBioMed research international2018

Oxidative Stress Markers Patients with Parotid Gland Tumors: A Pilot Study.

Pawel Sowa, Maciej Misiolek, Bartlomiej Pasinski, Grzegorz Bartosz, Miroslaw Soszynski, Monika Adamczyk-Sowa, Izabela Sadowska-Bartosz

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Heavy metal levels in malignant salivary gland tumours: a case-control study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Peroxisomes Are Highly Abundant and Heterogeneous in Human Parotid Glands.International journal of molecular sciences · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Pawel SowaDepartment of Otorhinolaryngology and Laryngological Oncology in Zabrze, Medical University of Silesia, Curie-Skłodowskiej St. 10, 41-800 Zabrze, Poland.ORCID 0000-0001-6179-2572
Maciej MisiolekDepartment of Otorhinolaryngology and Laryngological Oncology in Zabrze, Medical University of Silesia, Curie-Skłodowskiej St. 10, 41-800 Zabrze, Poland.
Bartlomiej PasinskiDepartment of Molecular Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska St. 141/143, 90-236 Lodz, Poland.
Grzegorz BartoszDepartment of Molecular Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska St. 141/143, 90-236 Lodz, Poland.ORCID 0000-0002-0347-0740
Miroslaw SoszynskiDepartment of Molecular Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska St. 141/143, 90-236 Lodz, Poland.
Monika Adamczyk-SowaDepartment of Neurology in Zabrze, Medical University of Silesia, 3-go Maja St. 13-15, 41-800 Zabrze, Poland.
Izabela Sadowska-BartoszDepartment of Analytical Biochemistry, Faculty of Biology and Agriculture, University of Rzeszow, Ul. Zelwerowicza 4, 35-601 Rzeszow, Poland.ORCID 0000-0001-9035-6833
Medical University of Silesia · PLUniversity of Łódź · PLUniversity of Rzeszów · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Salivary gland tumors account for 3-6% of tumors of the head and neck. About 80% of salivary gland tumors occur in parotid glands. Oxidative stress (OS) is implicated in the origin, development, and whole-body effects of various tumors. There are no data on the occurrence of OS in the parotid gland tumors. The aim of this study was to ascertain if whole-body OS accompanies parotid gland tumors, based first of all on oxidative modifications of blood serum proteins and other markers of OS in the serum of the patients. The group studied included 17 patients with pleomorphic adenoma, 9 patients with Warthin's tumor, 8 patients with acinic cell carcinoma, and 24 age-matched controls. We found increased concentration of interleukin 4 in patients with acinic cell carcinoma, decreased plasma thiols, increased AOPP concentration, and decreased FRAP of blood serum in all groups of the patients while protein oxidative modifications assessed fluorimetrically, protein carbonyls, protein nitration, malondialdehyde concentration, and serum ABTS

Indexed as

Oxidative StressAdvanced Oxidation Protein ProductsAgedBiomarkers, TumorFemaleHumansInterleukin-4MaleMiddle AgedNeoplasm ProteinsParotid NeoplasmsPilot ProjectsAdvanced Oxidation Protein ProductsBiomarkers, TumorIL4 protein, humanInterleukin-4Neoplasm Proteins

Identifiers

PMID29651432
PMCPMC5832034
OpenAlexW2786872550

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.