ReviewFrontiers in veterinary science2018
When the Nose Doesn't Know: Canine Olfactory Function Associated With Health, Management, and Potential Links to Microbiota.
Review in Frontiers in veterinary science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 113 citations in OpenAlex.
- Trial
- Canine "Sniffin' Sticks" enable behavioural olfactometry to complement neurological examination in dogs.Scientific reports · 2026Article
- Intestinal Dysbiosis Relating to Gut-Brain Axis and Behavior in Dogs: A Systematic Review with Text Mining Approach.Animals : an open access journal from MDPI · 2026Review
- What Makes Canine Search and Rescue Successful? Insights into Environmental, Management, and Personality Factors.Animals : an open access journal from MDPI · 2026Article
- Does Nose Work Training Affect Dog Executive Function and Physical Fitness in Humans and Dogs?Animals : an open access journal from MDPI · 2026Article
- The Role of Olfaction in Dogs: Evolution, Biology, and Human-Oriented Work.Animals : an open access journal from MDPI · 2026Review
- An overview of the benefits of animal-assisted interventions in medical and therapeutic contexts for human health: cognitive mechanisms, sensory perception and welfare considerations.Frontiers in veterinary science · 2026Review
- Behavioral components define operational suitability metric for detection dog success.Frontiers in veterinary science · 2026Article
- Nasal microbiota profiles are similar at two swabbing depths in healthy awake dogs.Frontiers in veterinary science · 2026Article
- Synthetic Cadaver Odorants and the Sulfur Gap: Linking Chemistry and Canine Olfaction in Human Remains Detection.Molecules (Basel, Switzerland) · 2025Review
- Sensing Dog Brain Reactions to Smell by AI Speckle Pattern Analysis.Journal of biophotonics · 2025Article
- Contributions and future potential of animal models for geroscience research on sensory systems.GeroScience · 2025Review
- Article
- Article
- PTSD assistance dogs: concerns for animal well-being, rights, and justice.Frontiers in veterinary science · 2025Article
- Canine olfactory detection of florfenicol residues in goat milk: a pilot study.Frontiers in veterinary science · 2025Article
- Effects of fecal microbial transplantation on police performance and transportation stress in Kunming police dogs.Applied microbiology and biotechnology · 2024Article
- From small to tall: breed-varied household pet dogs can be trained to detect Parkinson's Disease.Animal cognition · 2024Article
- Success in the Natural Detection Task is influenced by only a few factors generally believed to affect dogs' olfactory performance.Scientific reports · 2024Article
- Scent Detection Threshold of Trained Dogs toAnimals : an open access journal from MDPI · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The impact of health, management, and microbiota on olfactory function in canines has not been examined in review. The most important characteristic of the detection canine is its sense of smell. Olfactory receptors are primarily located on the ethmoturbinates of the nasal cavity. The vomeronasal organ is an additional site of odor detection that detects chemical signals that stimulate behavioral and/or physiological changes. Recent advances in the genetics of olfaction suggest that genetic changes, along with the unique anatomy and airflow of the canine nose, are responsible for the macrosmia of the species. Inflammation, alterations in blood flow and hydration, and systemic diseases alter olfaction and may impact working efficiency of detection canines. The scientific literature contains abundant information on the potential impact of pharmaceuticals on olfaction in humans, but only steroids, antibiotics, and anesthetic agents have been studied in the canine. Physical stressors including exercise, lack of conditioning, and high ambient temperature impact olfaction directly or indirectly in the canine. Dietary fat content, amount of food per meal, and timing of meals have been demonstrated to impact olfaction in mice and dogs. Gastrointestinal (GI) microbiota likely impacts olfaction via bidirectional communication between the GI tract and brain, and the microbiota is impacted by exercise, diet, and stress. The objective of this literature review is to discuss the specific effects of health, management, and microbiota shifts on olfactory performance in working canines.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.