ArticleMolecular autism2018
Analysis of neuroanatomical differences in mice with genetically modified serotonin transporters assessed by structural magnetic resonance imaging.
Article in Molecular autism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- Brain serotonin, oxytocin, and their interaction: Relevance for eating disorders.Journal of psychopharmacology (Oxford, England) · 2025Review
- Serotonin Signaling through Lipid Membranes.ACS chemical neuroscience · 2024Review
- Pervasive cortical and white matter anomalies in a mouse model for CHARGE syndrome.Journal of anatomy · 2023Article
- Constructing and optimizing 3D atlases from 2D data with application to the developing mouse brain.eLife · 2021Article
- Turning strains into strengths for understanding psychiatric disorders.Molecular psychiatry · 2020Review
- Serotonergic innervation of the amygdala is increased in autism spectrum disorder and decreased in Williams syndrome.Molecular autism · 2020Article
- Translational outcomes in a full gene deletion of ubiquitin protein ligase E3A rat model of Angelman syndrome.Translational psychiatry · 2020Article
- Ultrahigh-resolution MRI reveals structural brain differences in serotonin transporter knockout rats after sucrose and cocaine self-administration.Addiction biology · 2020Article
- A cross-disorder connectome landscape of brain dysconnectivity.Nature reviews. Neuroscience · 2019Review
- Enhanced Social Dominance and Altered Neuronal Excitability in the Prefrontal Cortex of Male KCC2b Mutant Mice.Autism research : official journal of the International Society for Autism Research · 2019Article
- Deformation-based Morphometry MRI Reveals Brain Structural Modifications in Living Mu Opioid Receptor Knockout Mice.Frontiers in psychiatry · 2018Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
Background: The serotonin (5-HT) system has long been implicated in autism spectrum disorder (ASD) as indicated by elevated whole blood and platelet 5-HT, altered platelet and brain receptor and transporter binding, and genetic linkage and association findings. Based upon work in genetically modified mice, 5-HT is known to influence several aspects of brain development, but systematic neuroimaging studies have not previously been reported. In particular, the 5-HT transporter (serotonin transporter, SERT; 5-HTT) gene, Methods: Using a 7-T MRI and deformation-based morphometry, we assessed neuroanatomical differences in an Results: Individually (same sex, same background, same genotype), the only differences found were in the female Conclusions: This work shows that an increase or decrease in SERT function has a significant effect on the neuroanatomy in 5-HT relevant regions, particularly the raphe nuclei. Notably, the
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.