Evidence map›Paper›PMID 29651289›Full record

ArticleFrontiers in immunology2018

Development and Characterization of an Endotoxemia Model in Zebra Fish.

Alan Y Hsu, Theodore Gurol, Tiago J P Sobreira, Sheng Zhang, Natalie Moore, Chufan Cai, Zhong-Yin Zhang, Qing Deng

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

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  11. Development and organization of the zebrafish intestinal epithelial stem cell niche.Developmental dynamics : an official publication of the American Association of Anatomists · 2020
    Article
  12. Phenotypical microRNA screen reveals a noncanonical role of CDK2 in regulating neutrophil migration.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Alan Y HsuDepartment of Biological Sciences, Purdue University, West Lafayette, IN, United States.
Theodore GurolDepartment of Biological Sciences, Purdue University, West Lafayette, IN, United States.
Tiago J P SobreiraBindley Bioscience Center, Purdue University, West Lafayette, IN, United States.
Sheng ZhangPurdue Institute for Drug Discovery, Purdue University, West Lafayette, IN, United States.
Natalie MooreDepartment of Biological Sciences, Purdue University, West Lafayette, IN, United States.
Chufan CaiDepartment of Biological Sciences, Purdue University, West Lafayette, IN, United States.
Zhong-Yin ZhangPurdue Institute for Drug Discovery, Purdue University, West Lafayette, IN, United States.
Qing DengDepartment of Biological Sciences, Purdue University, West Lafayette, IN, United States.
Purdue University West Lafayette · USCenter for Cancer Research · US

Funding

Transgenic Mouse Core Facility Shared Resource (TMCF-SR)P30CA023168 · NCI · PURDUE UNIVERSITY WEST LAFAYETTE · PI Andrea L Kasinski · 1985 to 2026
$43.4M
Role of microRNAs in neutrophil migrationR35GM119787 · NIGMS · PURDUE UNIVERSITY · PI Qing Deng · 2016 to 2026
$4.9M
Development of SHP2 inhibitors for targeted anti-cancer therapyR01CA207288 · NCI · PURDUE UNIVERSITY · PI ZHANG, ZHONG-YIN · 2017 to 2021
$2.3M
NCI NIH HHS P30 CA023168NCI NIH HHS R01 CA207288NIGMS NIH HHS R35 GM119787
6 · The paper itself

Abstract

Endotoxemia is a condition in which endotoxins enter the blood stream and cause systemic and sometimes lethal inflammation. Zebra fish provides a genetically tractable model organism for studying innate immunity, with additional advantages in live imaging and drug discovery. However, a

Indexed as

Disease Models, AnimalImmunity, InnateAnimalsBlood CirculationCell MovementCells, CulturedEndotoxemiaFish ProteinsGene Expression ProfilingHematopoiesisHumansImmunity, CellularInflammationLipopolysaccharidesMyeloid Differentiation Factor 88Protein Tyrosine Phosphatase, Non-Receptor Type 11Fish ProteinsLipopolysaccharidesMyeloid Differentiation Factor 88Protein Tyrosine Phosphatase, Non-Receptor Type 11endotoxemiaendotoxininflammationinnate immunitylipopolysaccharidezebra fish

Identifiers

PMID29651289
PMCPMC5884884
OpenAlexW2794980724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.