Evidence map›Paper›PMID 29651237›Full record

ArticleFrontiers in cellular neuroscience2018

DPP6 Loss Impacts Hippocampal Synaptic Development and Induces Behavioral Impairments in Recognition, Learning and Memory.

Lin Lin, Jonathan G Murphy, Rose-Marie Karlsson, Ronald S Petralia, Jakob J Gutzmann, Daniel Abebe, Ya-Xian Wang, Heather A Cameron, Dax A Hoffman

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
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  7. Article
  8. Review
  9. Frontiers in cell and developmental biology · 2025
    Article
  10. Article
  11. GWAS Identifies DPP6 as Risk Gene of Cognitive Decline in Parkinson's Disease.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Article
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  16. Review
  17. Review
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  19. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Lin LinMolecular Neurophysiology and Biophysics Section, Program in Developmental Neuroscience, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, United States.
Jonathan G MurphyMolecular Neurophysiology and Biophysics Section, Program in Developmental Neuroscience, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, United States.
Rose-Marie KarlssonSection on Neuroplasticity, National Institute of Mental Health, Bethesda, MD, United States.
Ronald S PetraliaAdvanced Imaging Core, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, United States.
Jakob J GutzmannMolecular Neurophysiology and Biophysics Section, Program in Developmental Neuroscience, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, United States.
Daniel AbebeMolecular Neurophysiology and Biophysics Section, Program in Developmental Neuroscience, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, United States.
Ya-Xian WangAdvanced Imaging Core, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, United States.
Heather A CameronSection on Neuroplasticity, National Institute of Mental Health, Bethesda, MD, United States.
Dax A HoffmanMolecular Neurophysiology and Biophysics Section, Program in Developmental Neuroscience, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, United States.
Eunice Kennedy Shriver National Institute of Child Health and Human Development · USNational Institute of Mental Health · USNational Institute on Deafness and Other Communication Disorders · USNational Institutes of Health · US

Funding

Neurogenesis In The Adult BrainZIAMH002784 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI CAMERON, HEATHER A · 2009 to 2025
$29.7M
Potassium Channels and Dendritic Function in Hippocampal Pyramidal NeuronsZIAHD008755 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI HOFFMAN, DAX A · 2009 to 2025
$29.6M
Advanced Imaging CoreZICDC000081 · NIDCD · NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS · PI WINKLER, DENNIS · 2012 to 2025
$17.4M
SYNTACTIC REPRESENTATIONSP50DC000081 · NIDCD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI NAESER, MARGARET A · 1992 to 2001
$989k
Intramural NIH HHS ZIC DC000081NIDCD NIH HHS P50 DC000081
6 · The paper itself

Abstract

DPP6 is well known as an auxiliary subunit of Kv4-containing, A-type K

Indexed as

autism spectrum disorderDPP6learning and memoryneurodevelopment

Identifiers

PMID29651237
PMCPMC5884885
OpenAlexW2795285287

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.