Evidence map›Paper›PMID 29651010›Full record

ArticleScientific reports2018

Dietary supplementation with flaxseed meal and oat hulls modulates intestinal histomorphometric characteristics, digesta- and mucosa-associated microbiota in pigs.

S P Ndou, H M Tun, E Kiarie, M C Walsh, E Khafipour, C M Nyachoti

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 37 citations in OpenAlex.

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  17. Applied and environmental microbiology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

S P NdouDepartment of Animal Science, University of Manitoba, Winnipeg, MB, Canada, R3T 2N2.
H M TunDepartment of Animal Science, University of Manitoba, Winnipeg, MB, Canada, R3T 2N2.ORCID 0000-0001-7597-5062
E KiarieDepartment of Animal Science, University of Manitoba, Winnipeg, MB, Canada, R3T 2N2.
M C WalshDuPont Industrial Biosciences-Danisco Animal Nutrition, Marlborough, Wiltshire, United Kingdom, SN8 1XN.
E KhafipourDepartment of Animal Science, University of Manitoba, Winnipeg, MB, Canada, R3T 2N2.
C M NyachotiDepartment of Animal Science, University of Manitoba, Winnipeg, MB, Canada, R3T 2N2. Martin_Nyachoti@umanitoba.ca.
University of Manitoba · CADuPont (United Kingdom) · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The establishment of a healthy gastrointestinal milieu may not only offer an opportunity to reduce swine production costs but could also open the way for a lifetime of human health improvement. This study investigates the effects of feeding soluble fibre from flaxseed meal-containing diet (FM) and insoluble fibre from oat hulls-containing diet (OH) on histomorphological characteristics, digesta- and mucosa-associated microbiota and their associations with metabolites in pig intestines. In comparison with the control (CON) and OH diets, the consumption of FM increased (P < 0.001) the jejunal villi height (VH) and the ratio of VH to crypt depths. The PERMANOVA analyses showed distinct (P < 0.05) microbial communities in ileal digesta and mucosa, and caecal mucosa in CON and FM-diets fed pigs compared to the OH diet-fed pigs. The predicted functional metagenomes indicated that amino acids and butanoate metabolism, lysine degradation, bile acids biosynthesis, and apoptosis were selectively enhanced at more than 2.2 log-folds in intestinal microbiota of pigs fed the FM diet. Taken together, flaxseed meal and oat hulls supplementation in growing pigs' diets altered the gastrointestinal development, as well as the composition and function of microbial communities, depending on the intestinal segment and physicochemical property of the dietary fibre source.

Indexed as

AvenaDietary SupplementsFlaxAnimalsBile Acids and SaltsDietary FiberDigestionGastrointestinal MicrobiomeGastrointestinal TractIntestinesMetagenomeSwineBile Acids and SaltsDietary Fiber

Identifiers

PMID29651010
PMCPMC5897541
OpenAlexW2797357504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.