Evidence map›Paper›PMID 29650696›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

NPY Induces Stress Resilience via Downregulation of

Heika Silveira Villarroel, Maria Bompolaki, James P Mackay, Ana Pamela Miranda Tapia, Sheldon D Michaelson, Randy J Leitermann, Robert A Marr, Janice H Urban, William F Colmers

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Neuropeptide Y and Pain: Insights from Brain Research.ACS pharmacology & translational science · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Central Amygdala Projections to Lateral Hypothalamus Mediate Avoidance Behavior in Rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  15. Article
  16. Article
  17. Neuropeptide Y Expression Defines a Novel Class of GABAergic Projection Neuron in the Inferior Colliculus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  18. Contribution of NPY YThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Heika Silveira VillarroelDepartment of Pharmacology, University of Alberta, Edmonton, Alberta, Canada T6G 2H7.
Maria BompolakiDepartment of Physiology and Biophysics, and.ORCID 0000-0001-7517-2374
James P MackayDepartment of Pharmacology, University of Alberta, Edmonton, Alberta, Canada T6G 2H7.
Ana Pamela Miranda TapiaDepartment of Pharmacology, University of Alberta, Edmonton, Alberta, Canada T6G 2H7.
Sheldon D MichaelsonDepartment of Pharmacology, University of Alberta, Edmonton, Alberta, Canada T6G 2H7.
Randy J LeitermannDepartment of Physiology and Biophysics, and.
Robert A MarrDepartment of Neuroscience, Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois 60064.
Janice H UrbanDepartment of Physiology and Biophysics, and.
William F ColmersDepartment of Pharmacology, University of Alberta, Edmonton, Alberta, Canada T6G 2H7, william.colmers@ualberta.ca.
University of Alberta · CAInstitute of Molecular Biology and Biophysics · RURosalind Franklin University of Medicine and Science · US

Funding

Mechanisms Underlying Stress ResilienceR01MH090297 · NIMH · ROSALIND FRANKLIN UNIV OF MEDICINE & SCI · PI URBAN, JANICE H · 2010 to 2014
$1.7M
Neuropeptide circuits and stress regulation in the basolateral amygdalaR56MH081152 · NIMH · ROSALIND FRANKLIN UNIV OF MEDICINE & SCI · PI URBAN, JANICE H · 2009 to 2009
$430k
CIHR MT10520NIMH NIH HHS R01 MH090297NIMH NIH HHS R56 MH081152
6 · The paper itself

Abstract

Neuropeptide Y (NPY) expression is tightly linked with the development of stress resilience in rodents and humans. Local NPY injections targeting the basolateral amygdala (BLA) produce long-term behavioral stress resilience in male rats via an unknown mechanism. Previously, we showed that activation of NPY Y

Indexed as

AmygdalaAnimalsAnxietyDown-RegulationElectrophysiological PhenomenaExcitatory Postsynaptic PotentialsGene Knockdown TechniquesHyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsInterpersonal RelationsMaleMicroinjectionsNeuronsNeuropeptide YPotassium ChannelsPotassium Channels, Inwardly RectifyingRatsHcn1 protein, mouseHcn1 protein, ratHyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsNeuropeptide YPotassium ChannelsPotassium Channels, Inwardly RectifyingCRFHCN1lentivirusneuropeptide YshRNAsocial interaction

Identifiers

PMID29650696
PMCPMC5943978
OpenAlexW2797258087

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.