Evidence map›Paper›PMID 29650680›Full record

ArticleThe EMBO journal2018

Cell type-specific regulation of ciliary transition zone assembly in vertebrates.

Antonia Wiegering, Renate Dildrop, Lisa Kalfhues, André Spychala, Stefanie Kuschel, Johanna Maria Lier, Thomas Zobel, Stefanie Dahmen, Tristan Leu, Andreas Struchtrup and 6 more

Open access · hybridAbstract read
In one paragraph

Article in The EMBO journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 75 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Antonia WiegeringInstitute for Animal Developmental and Molecular Biology, Heinrich Heine University, Düsseldorf, Germany.
Renate DildropInstitute for Animal Developmental and Molecular Biology, Heinrich Heine University, Düsseldorf, Germany.
Lisa KalfhuesInstitute for Animal Developmental and Molecular Biology, Heinrich Heine University, Düsseldorf, Germany.
André SpychalaInstitute for Animal Developmental and Molecular Biology, Heinrich Heine University, Düsseldorf, Germany.
Stefanie KuschelInstitute for Animal Developmental and Molecular Biology, Heinrich Heine University, Düsseldorf, Germany.
Johanna Maria LierInstitute for Animal Developmental and Molecular Biology, Heinrich Heine University, Düsseldorf, Germany.
Thomas ZobelCenter for Advanced Imaging (CAi), Heinrich Heine University, Düsseldorf, Germany.
Stefanie DahmenInstitute for Animal Developmental and Molecular Biology, Heinrich Heine University, Düsseldorf, Germany.
Tristan LeuInstitute for Animal Developmental and Molecular Biology, Heinrich Heine University, Düsseldorf, Germany.
Andreas StruchtrupInstitute for Animal Developmental and Molecular Biology, Heinrich Heine University, Düsseldorf, Germany.
Flora LegendreINSERM, U983, Hôpital Necker-Enfants Malades, Paris, France.
Christine VesqueParis-Seine (IBPS) - Developmental Biology Laboratory, Institut de Biologie, CNRS, UMR7622, INSERM U1156, Paris, France.
Sylvie Schneider-MaunouryParis-Seine (IBPS) - Developmental Biology Laboratory, Institut de Biologie, CNRS, UMR7622, INSERM U1156, Paris, France.
Sophie SaunierINSERM, U983, Hôpital Necker-Enfants Malades, Paris, France.
Ulrich RütherInstitute for Animal Developmental and Molecular Biology, Heinrich Heine University, Düsseldorf, Germany.
Christoph GerhardtInstitute for Animal Developmental and Molecular Biology, Heinrich Heine University, Düsseldorf, Germany Christoph.Gerhardt@hhu.de.ORCID 0000-0002-6340-549X
Heinrich Heine University Düsseldorf · DECentre National de la Recherche Scientifique · FRDélégation Paris 5 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ciliopathies are life-threatening human diseases caused by defective cilia. They can often be traced back to mutations of genes encoding transition zone (TZ) proteins demonstrating that the understanding of TZ organisation is of paramount importance. The TZ consists of multimeric protein modules that are subject to a stringent assembly hierarchy. Previous reports place Rpgrip1l at the top of the TZ assembly hierarchy in

Indexed as

Adaptor Proteins, Signal TransducingAnimalsAntigens, NeoplasmCarrier ProteinsCell Cycle ProteinsCell Membrane StructuresCells, CulturedCiliaCytoskeletal ProteinsEmbryo, MammalianFibroblastsHEK293 CellsHumansMiceMice, Inbred C57BLMice, KnockoutAdaptor Proteins, Signal TransducingAntigens, NeoplasmCarrier ProteinsCell Cycle ProteinsCep290 protein, mouseCytoskeletal ProteinsFtm protein, mouseInvs protein, mouseNphp1 protein, mouseNPHP4 protein, mouseNuclear ProteinsProteinsRPGRIP1L protein, humanRpgrip1 protein, mouseTranscription FactorsciliaciliopathiesNphpRpgrip1Rpgrip1l

Identifiers

PMID29650680
PMCPMC5978567
OpenAlexW2798068251

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.