Evidence map›Paper›PMID 29650676›Full record

ArticleClinical science (London, England : 1979)2018

Sodium bicarbonate loading limits tubular cast formation independent of glomerular injury and proteinuria in Dahl salt-sensitive rats.

Sarah C Ray, Bansari Patel, Debra L Irsik, Jingping Sun, Hiram Ocasio, Gene R Crislip, Chunhua H Jin, JianKang Chen, Babak Baban, Aaron J Polichnowski and 1 more

Open access · greenAbstract read
In one paragraph

Article in Clinical science (London, England : 1979), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The immunomodulatory effect of oral NaHCOJournal of neuroinflammation · 2024
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Sarah C RayDepartment of Physiology, Medical College of Georgia, Augusta University.
Bansari PatelDepartment of Physiology, Medical College of Georgia, Augusta University.
Debra L IrsikDepartment of Physiology, Medical College of Georgia, Augusta University.
Jingping SunDepartment of Physiology, Medical College of Georgia, Augusta University.
Hiram OcasioDepartment of Physiology, Medical College of Georgia, Augusta University.
Gene R CrislipDepartment of Physiology, Medical College of Georgia, Augusta University.
Chunhua H JinDepartment of Medicine, Division of Nephrology, University of Alabama Birmingham, Alabama, USA.
JianKang ChenDepartment of Cell Biology and Anatomy, Augusta University, Augusta, Georgia, USA.
Babak BabanDepartment of Oral Biology, Augusta University, Augusta, Georgia, USA.
Aaron J PolichnowskiDepartment of Biological Sciences, East Tennessee State University, Johnson City, Tennessee, USA.
Paul M O'ConnorDepartment of Physiology, Medical College of Georgia, Augusta University paoconnor@augusta.edu.
Augusta University · USEast Tennessee State University · USUniversity of Alabama · US

Funding

Mechanisms Underlying the Susceptibility and Severity of Acute Kidney InjuryR01DK114328 · NIDDK · AUGUSTA UNIVERSITY · PI CHEN, JIAN-KANG · 2017 to 2021
$1.7M
Role of HV1 in development of salt-sensitive hypertension and renal injuryR01DK099548 · NIDDK · AUGUSTA UNIVERSITY · PI O'CONNOR, PAUL MICHAEL · 2014 to 2018
$1.6M
NIDDK NIH HHS R01 DK099548NIDDK NIH HHS R01 DK114328
6 · The paper itself

Abstract

Sodium bicarbonate (NaHCO

Indexed as

AcidsAnimalsBlood GlucoseDisease Models, AnimalFibrosisGlomerulosclerosis, Focal SegmentalHemodynamicsHydrogen-Ion ConcentrationIon ChannelsKidney TubulesMaleProteinuriaRats, Inbred DahlRats, Mutant StrainsSodium BicarbonateSodium Chloride, DietaryAcidsBlood GlucoseHv1 proton channel, ratIon ChannelsSodium BicarbonateSodium Chloride, DietaryAlkaliKidneyProton ChannelSalt-SensitiveThick Ascending Limb

Identifiers

PMID29650676
PMCPMC7473054
OpenAlexW2797980613

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.