Trial reportThe European respiratory journal2018
Low-dose computed tomography for the diagnosis of pneumonia in elderly patients: a prospective, interventional cohort study.
Trial report in The European respiratory journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
51 citing papers in PubMed.
- Accuracy of a score predicting the presence of an atypical pathogen in hospitalized patients with moderately severe community-acquired pneumonia.BMC infectious diseases · 2022Trial
- Accuracy of comprehensive PCR analysis of nasopharyngeal and oropharyngeal swabs for CT-scan-confirmed pneumonia in elderly patients: a prospective cohort study.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2019Trial
- Factors Associated with 30-Day Non-Return to Pre-Hospital Residence in Older Patients Hospitalized with Pneumonia or Lower Respiratory Tract Infection: The Role of Serum Albumin and Early Treatment Failure.Geriatrics (Basel, Switzerland) · 2026Article
- Diagnostic discordance and differential diagnoses of community-acquired pneumonia in the emergency department.BMC emergency medicine · 2026Article
- Diagnostic accuracy of chest radiograph versus computed tomography for suspected pneumonia in obese patients.Emergency radiology · 2026Article
- Guidelines for the Initial Assessment of Respiratory Distress in the Emergency Department.Annals of intensive care · 2026Article
- The Usefulness and Limitations of Radiologic Findings for Diagnosis of Infectious Diseases: A Call for Antimicrobial Stewardship.Infection & chemotherapy · 2025Review
- A Host-Protein Test for Differentiating Bacterial From Viral Infection: Diagnostic Accuracy in Elderly Patients.Journal of the American College of Emergency Physicians open · 2025Article
- Cost effectiveness of imaging strategies in the emergency department for the diagnostic workup of community-acquired pneumonia: a real-life retrospective study.Health economics review · 2025Article
- FLPneXAINet: Federated deep learning and explainable AI for improved pneumonia prediction utilizing GAN-augmented chest X-ray data.PloS one · 2025Article
- Enhanced Pneumonia Detection in Chest X-Rays Using Hybrid Convolutional and Vision Transformer Networks.Current medical imaging · 2025Article
- A Review on Risk Factors, Traditional Diagnostic Techniques, and Biomarkers for Pneumonia Prognostication and Management in Diabetic Patients.Diseases (Basel, Switzerland) · 2024Review
- An AI deep learning algorithm for detecting pulmonary nodules on ultra-low-dose CT in an emergency setting: a reader study.European radiology experimental · 2024Article
- Article
- Improving prognostication of pneumonia among elderly patients: usefulness of suPAR.BMC geriatrics · 2024Observational
- Can clinicians identify community-acquired pneumonia on ultralow-dose CT? A diagnostic accuracy study.Scandinavian journal of trauma, resuscitation and emergency medicine · 2024Article
- Guidelines for Antibiotics Prescription in Critically Ill Patients.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024Article
- Article
- XRayWizard: Reconstructing 3-D lung surfaces from a single 2-D chest x-ray image via Vision Transformer.Medical physics · 2024Article
- Imaging in pulmonary infections of immunocompetent adult patients.Breathe (Sheffield, England) · 2024Review
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Authors and funding
20 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The diagnosis of pneumonia is challenging. Our objective was to assess whether low-dose computed tomography (LDCT) modified the probability of diagnosing pneumonia in elderly patients.We prospectively included patients aged over 65 years with a suspicion of pneumonia treated with antimicrobial therapy (AT). All patients had a chest radiograph and LDCT within 72 h of inclusion. The treating clinician assessed the probability of pneumonia before and after the LDCT scan using a Likert scale. An adjudication committee retrospectively rated the probability of pneumonia and was considered as the reference for diagnosis. The main outcome was the difference in the clinician's pneumonia probability estimates before and after LDCT and the proportion of modified diagnoses which matched the reference diagnosis (the net reclassification improvement (NRI)).A total of 200 patients with a median age of 84 years were included. After LDCT, the estimated probability of pneumonia changed in 90 patients (45%), of which 60 (30%) were downgraded and 30 (15%) were upgraded. The NRI was 8% (NRI event (-6%) + NRI non-event (14%)).LDCT modified the estimated probability of pneumonia in a substantial proportion of patients. It mostly helped to exclude a diagnosis of pneumonia and hence to reduce unnecessary AT.
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