Evidence map›Paper›PMID 29650053›Full record

Observational studyJournal of cardiothoracic surgery2018

Volume of mural thrombus plays a role in the elevation of inflammatory markers after endovascular aortic repair.

Jae Hang Lee, Jin-Ho Choi, Eung-Joong Kim

Abstract readObservational Study
In one paragraph

Observational study in Journal of cardiothoracic surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jae Hang LeeDepartment of thoracic and cardiovascular surgery, Dongguk University Ilsan Hospital, Goyang, Gyeonggi, South Korea. truemed@hotmail.com.ORCID http://orcid.org/0000-0003-4769-5340
Jin-Ho ChoiDepartment of thoracic and cardiovascular surgery, Dongguk University Ilsan Hospital, Goyang, Gyeonggi, South Korea.
Eung-Joong KimDepartment of thoracic and cardiovascular surgery, Dongguk University Ilsan Hospital, Goyang, Gyeonggi, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough systemic inflammatory responses are common after endovascular aortic repair (EVAR), its etiology remains uncertain. It is normally well tolerated and has a benign course. This study was undertaken to investigate the possible etiology of post-EVAR inflammation by measuring volumes of chronic mural thrombus and fresh thrombus.

methodsThe subjects of this study included 34 patients who underwent EVAR from February 2012 to July 2017. Inflammatory markers in all the patients were evaluated before surgery, using the highest value among the laboratory data up to 5 days after surgery, and postoperative computed tomographic angiography (CTA) was taken for all of them before their discharging. Volumes of mural thrombus and fresh thrombus were calculated by CTA. The mean interval from surgery to immediate postoperative CTA was estimated as 6.8 ± 4.0 days.

resultsAfter undergoing EVAR, white blood cell (WBC) (p < 0.01), C-reactive protein (CRP) (p < 0.01) and erythrocyte sedimentation rate (ESR) (p = 0.01) were significantly elevated. Two groups were defined according to the post-implantation syndrome (PIS) by the criteria of systemic inflammatory response syndrome (SIRS);no significant differences were observed in any factors between the two groups. Classification of two groups by the criteria of increasing WBC and CRP revealed that inflammatory markers were significantly enhanced as the volume of mural thrombus increased (p = 0.03). However, no significant risk factor was found in view of aneurysmal growth after EVAR.

conclusionVolume of mural thrombus is an important risk factor for the elevation of inflammatory markers after EVAR.

Indexed as

AgedAged, 80 and overAortic AneurysmBiomarkersBlood Vessel Prosthesis ImplantationComputed Tomography AngiographyC-Reactive ProteinEndovascular ProceduresFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsSystemic Inflammatory Response SyndromeThrombosisBiomarkersC-Reactive ProteinAortic aneurysmEndovascular aortic repairInflammationThrombus

Identifiers

PMID29650053
PMCPMC5897938

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.