Evidence map›Paper›PMID 29650030›Full record

ArticleJournal of translational medicine2018

Harnessing Qatar Biobank to understand type 2 diabetes and obesity in adult Qataris from the First Qatar Biobank Project.

Ehsan Ullah, Raghvendra Mall, Reda Rawi, Naima Moustaid-Moussa, Adeel A Butt, Halima Bensmail

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal of translational medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

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  7. Systems biology analysis of human genomes points to key pathways conferring spina bifida risk.Proceedings of the National Academy of Sciences of the United States of America · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Ehsan UllahQatar Computing Research Institute, Hamad Bin Khalifa University, Doha, Qatar.
Raghvendra MallQatar Computing Research Institute, Hamad Bin Khalifa University, Doha, Qatar.
Reda RawiQatar Computing Research Institute, Hamad Bin Khalifa University, Doha, Qatar.
Naima Moustaid-MoussaObesity Research Cluster (ORC), Nutrigenomics, Inflammation and Obesity Research (NIOR) Laboratory, Texas Tech University, 1301 Akron Street, Lubbock, TX, 79409-1270, USA.
Adeel A ButtDepartment of Medicine, Weill Cornell Medical College, Doha, Qatar.
Halima BensmailQatar Computing Research Institute, Hamad Bin Khalifa University, Doha, Qatar. hbensmail@hbku.edu.qa.
Hamad bin Khalifa University · QAHamad Medical Corporation · QANational Institute of Allergy and Infectious Diseases · USTexas Tech University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHuman tissues are invaluable resources for researchers worldwide. Biobanks are repositories of such human tissues and can have a strategic importance for genetic research, clinical care, and future discoveries and treatments. One of the aims of Qatar Biobank is to improve the understanding and treatment of common diseases afflicting Qatari population such as obesity and diabetes.

methodsIn this study we apply a panorama of state-of-the-art statistical methods and machine learning algorithms to investigate associations and risk factors for diabetes and obesity on a sample of 1000 Qatari population.

resultsRegarding diabetes, we identified pronounced associations and risk factors in Qatari population including magnesium, chloride, c-peptide of insulin, insulin, and uric acid. Similarly, for obesity, significant associations and risk factors include insulin, c-peptide of insulin, albumin, and uric acid. Moreover, our study has revealed interactions of hypomagnesemia with HDL-C, triglycerides, and free thyroxine.

conclusionsOur study strongly confirms known associations and risk factors associated with diabetes and obesity in Qatari population as previously found in other population studies in different parts of the world. Moreover, interactions of hypomagnesemia with other associations and risk factors merit further investigations.

Indexed as

Biological Specimen BanksAdultCase-Control StudiesDiabetes Mellitus, Type 2HumansMachine LearningMiddle AgedMultivariate AnalysisObesityPrincipal Component AnalysisProportional Hazards ModelsQatarSurvival AnalysisBiostatisticsDiabetesEpidemiologyMachine learningObesityQatar Biobank

Identifiers

PMID29650030
PMCPMC5898076
OpenAlexW2805887458

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.