ReviewBiomedical engineering online2018
Technologies to monitor the health of loaded skin tissues.
Review in Biomedical engineering online, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07560683 (Investigation of Skin Barrier Function Using Biosensor Methods in Risky Skin Regions and Developed Pressure Injuries in Intensive Care Patients, and Identification of Influencing Factors), which is not on this map. Cited by 33 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Investigation of Skin Barrier Function Using Biosensor Methods in Risky Skin Regions and Developed Pressure Injuries in Intensive Care Patients, and Identification of Influencing Factors: The SKIN-BAR Project
Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review of movement monitoring devices to aid the prediction of pressure ulcers in at-risk adults.International wound journal · 2023Pooled it
- The Efficacy and Safety of Botulinum Toxin Injections in Preventing Postoperative Scars and Improving Scar Quality: A Systematic Review and Meta-Analysis.Aesthetic plastic surgery · 2021Pooled it
- A Randomised Cross-Over Study to Evaluate the Physiological Effects of Internal Air Pressure Changes in Advanced Support Surface Design.International wound journal · 2025Trial
- Effects of loading and prophylactic dressings on the sacral and heel skin: An exploratory cross-over trial.International wound journal · 2021Trial
- Lateral Pressure Application to the Seated Buttocks Largely Maintains Transcutaneous Gas Tensions at the Ischial Tuberosity in a Healthy Cohort.International wound journal · 2026Article
- Observational
- Temporal Inflammatory Profile in Skin Surface after Oronasal Mask Application.Acta dermato-venereologica · 2026Article
- Skin Epidermal and Microvascular Properties at the Sacrum and Heel Assessed with Optical Coherence Tomography.Skin pharmacology and physiology · 2026Article
- Erratum: A Comprehensive Analysis of Dermatological Manifestations in Lower Limb Para-Athletes.Archives of clinical and medical case reports · 2026Article
- A Benchtop Evaluation of Cervical Collar Design and Strap Tension.Medical devices (Auckland, N.Z.) · 2026Article
- Repeated Pressure and Shear Stress at the Posterior Heel Following Localized Skin Cooling: Protocol for a Repeated Measures Cohort Study.JMIR research protocols · 2025Article
- The use of a protein network analysis to explore the complexity of early skin inflammation after oronasal mask application- A pilot study.Scientific reports · 2024Article
- Strategies in surface engineering for the regulation of microclimates in skin-medical product interactions.Heliyon · 2024Review
- Spatial and temporal changes in biophysical skin parameters over a category I pressure ulcer.International wound journal · 2023Article
- Inflammatory biomarkers in sebum for identifying skin damage in patients with a Stage I pressure ulcer in the pelvic region: A single centre observational, longitudinal cohort study with elderly patients.International wound journal · 2023Observational
- A Wearable Insole System to Measure Plantar Pressure and Shear for People with Diabetes.Sensors (Basel, Switzerland) · 2023Article
- Biomarkers for the early detection of pressure ulcers in the intensive care setting: A comparison between sub-epidermal moisture measurements and interleukin-1α.International wound journal · 2023Observational
- An evaluation of mechanical and biophysical skin parameters at different body locations.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2023Article
- Article
- Assessing Socket Fit Effects on Pressure and Shear at a Transtibial Residuum/Socket Interface.Applied bionics and biomechanics · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
There are many situations where the skin and underlying soft tissues are compromised by mechanical loading in the form or pressure, or pressure in combination with shear. If sustained, this can lead to damage in the tissues particularly adjacent to bony prominences, resulting in chronic wounds. An array of bioengineering technologies have been adopted to assess the integrity of loaded soft tissues. This paper aims to review these approaches for the quantification, simulation and early detection of mechanically-induced skin damage. The review considers different measurements at the interface between the skin and support surface/medical device, involving pressure, shear, friction and the local microclimate. The potential of the techniques to monitor the physiological response of the skin to these external stimuli including biophysical measurement devices and sampling of biofluids are critically analysed. In addition, it includes an analysis of medical imaging technologies and computational modelling to provide a means by which tissue deformation can be quantified and thresholds for tissue damage defined. Bioengineering measurement and imaging technologies have provided an insight into the temporal status of loaded skin. Despite the advances in technology, to date, the translation to clinical tools which are robust and cost effective has been limited. There is a need to adapt existing technologies and simulation platforms to enable patients, carers and clinicians to employ appropriate intervention strategies to minimise soft tissue damage.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.