Trial reportBMC neurology2018
Protocol for promoting recovery optimization of walking activity in stroke (PROWALKS): a randomized controlled trial.
Trial report in BMC neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02835313 (Promoting Recovery Optimization With WALKing Exercise After Stroke), which is not on this map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Promoting Recovery Optimization With WALKing Exercise After Stroke
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Interventions for reducing sedentary behaviour in people with stroke.The Cochrane database of systematic reviews · 2021Pooled it
- Physical fitness training for stroke patients.The Cochrane database of systematic reviews · 2020Pooled it
- Quantifying Exercise Intensity to Predict Changes in Walking Capacity in Individuals with Chronic Stroke.Archives of physical medicine and rehabilitation · 2026Trial
- Is training speed an accurate predictor of who attains a minimal clinically important difference in the six-minute walk test in people with chronic stroke?Topics in stroke rehabilitation · 2025Trial
- Maintenance of Improvements in Walking Activity in Individuals with Chronic Stroke: Follow-Up From the PROWALKS Randomized Controlled Trial.Neurorehabilitation and neural repair · 2025Trial
- Effectiveness of a rehabilitation program involving functional proprioceptive stimulation for postural control and motor recovery among stroke patients: a double-blinded, randomized, controlled trial.Journal of neuroengineering and rehabilitation · 2025Trial
- Matching Clinical Profiles With Interventions to Optimize Daily Stepping in People With Stroke.Physical therapy · 2025Trial
- Cardiopulmonary exercise tests in people with chronic stroke: Interpretation and clinical application.Clinical rehabilitation · 2025Trial
- Trial
- Beyond Physical Capacity: Factors Associated With Real-world Walking Activity After Stroke.Archives of physical medicine and rehabilitation · 2021Trial
- Impact of Individual Factors on Exercise Dose During a Walking Intervention in People With Stroke.Journal of neurologic physical therapy : JNPT · 2025Article
- Using Exercise Intensity to Predict a Minimal Clinically Important Difference in the Six-Minute Walk Test in People with Chronic Stroke.medRxiv : the preprint server for health sciences · 2025Article
- Interventions to improve outdoor mobility among people living with disabilities: A systematic review.Campbell systematic reviews · 2024Review
- Quantifying the effects of sleep on sensor-derived variables from upper limb accelerometry in people with and without upper limb impairment.Journal of neuroengineering and rehabilitation · 2024Article
- Review
- Beyond steps per day: other measures of real-world walking after stroke related to cardiovascular risk.Journal of neuroengineering and rehabilitation · 2022Article
- Relationships Among Environmental Variables, Physical Capacity, Balance Self-Efficacy, and Real-World Walking Activity Post-Stroke.Neurorehabilitation and neural repair · 2022Article
- A machine learning approach to identifying important features for achieving step thresholds in individuals with chronic stroke.PloS one · 2022Article
- [Causal relationship between physical exercise and risk of ischemic stroke recurrence based on the potential outcome theory].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021Article
- Enriched environment boosts the post-stroke recovery of neurological function by promoting autophagy.Neural regeneration research · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundStroke survivors are more physically inactive than even the most sedentary older adults, and low activity is associated with increased risk of recurrent stroke, medical complications, and mortality. We hypothesize that the combination of a fast walking intervention that improves walking capacity, with a step activity monitoring program that facilitates translation of gains from the clinic to the "real-world", would generate greater improvements in real world walking activity than with either intervention alone.
methodsUsing a single-blind randomized controlled experimental design, 225 chronic (> 6 months) stroke survivors complete 12 weeks of fast walking training, a step activity monitoring program or a fast walking training + step activity monitoring program. Main eligibility criteria include: chronic ischemic or hemorrhagic stroke (> 6 months post), no evidence of cerebellar stroke, baseline walking speed between 0.3 m/s and 1.0 m/s, and baseline average steps / day < 8000. The primary (steps per day), secondary (self-selected and fastest walking speed, walking endurance, oxygen consumption) and exploratory (vascular events, blood lipids, glucose, blood pressure) outcomes are assessed prior to initiating treatment, after the last treatment and at a 6 and 12-month follow-up. Moderation of the changes in outcomes by baseline characteristics are evaluated to determine for whom the interventions are effective. DISCUSSION: Following completion of this study, we will not only understand the efficacy of the interventions and the individuals for which they are effective, we will have the necessary information to design a study investigating the secondary prevention benefits of improved physical activity post-stroke. This study is, therefore, an important step in the development of both rehabilitative and secondary prevention guidelines for persons with stroke.
trial registrationClinicalTrials.gov Identifier: NCT02835313 . First Posted: July 18, 2016.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.