Evidence map›Paper›PMID 29649831›Full record

ArticleUrologia internationalis2018

What Is the Best Way to Prepare A Buccal Mucosa Graft for Urethroplasty? A Histology-Based Preliminary Report.

André G Cavalcanti, Carlos F Restrepo, Michele Simões, Waldemar S Costa, Francisco J B Sampaio, Diogo B de Souza

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Article in Urologia internationalis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

André G CavalcantiDepartment of General and Specialized Surgery, Federal University of the State of Rio de Janeiro, Rio de Janeiro, Brazil.
Carlos F RestrepoDepartment of General and Specialized Surgery, Federal University of the State of Rio de Janeiro, Rio de Janeiro, Brazil.
Michele SimõesUrogenital Research Unit, Rio de Janeiro State University, Rio de Janeiro, Brazil.
Waldemar S CostaUrogenital Research Unit, Rio de Janeiro State University, Rio de Janeiro, Brazil.
Francisco J B SampaioUrogenital Research Unit, Rio de Janeiro State University, Rio de Janeiro, Brazil.
Diogo B de SouzaUrogenital Research Unit, Rio de Janeiro State University, Rio de Janeiro, Brazil.
Universidade do Estado do Rio de Janeiro · BRUniversidade Federal do Estado do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the histological characteristics of buccal mucosa samples prepared using different dissection techniques.

methodsThe buccal mucosae harvested from 9 men submitted to a substitution urethroplasty were used in this study. Biopsy specimens of buccal mucosae were grouped according to the macroscopic appearance after dissection: Group 1 - yellowish appearance (minimal dissection), Group 2 - whitish appearance (more aggressive dissection), and Group 3 - translucent appearance (ultra-aggressive dissection). The biopsy specimens were evaluated using histomorphometric techniques. The thicknesses of the graft, epithelium, and sub-epithelial connective tissue were compared.

resultsThe samples from Group 3 and Groups 2 and 3 presented lower total and lower sub-epithelial connective tissue thickness, respectively, when compared with Group 1. The epithelial thickness was not affected by the dissection method. Muscular and adipose tissues were present in 77 and 55% of samples from Group 1, respectively, whereas these were observed in 44 and 22% of samples from Group 2 respectively. The muscular tissue was observed in 11% of the cases, and the adipose tissue was not observed in samples prepared with ultra-aggressive dissection.

conclusionWe conclude that an intermediate graft dissection (whitish appearance, as performed in Group 2) presents the best balance between subepithelial connective tissue preservation and adipose and muscle tissue removal.

Indexed as

Adipose TissueAdultAgedBiopsyHumansMaleMiddle AgedMouth MucosaMusclesPenisPlastic Surgery ProceduresSurgical FlapsUrethraUrethral StrictureUrologic Surgical Procedures, MaleYoung AdultBuccal mucosaGraftUrethraUrethroplatsy

Identifiers

PMID29649831
OpenAlexW2807727188

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.