Evidence map›Paper›PMID 29649378›Full record

ArticleMetabolic syndrome and related disorders2018

Poor Sleep Quality is Associated with Insulin Resistance in Postmenopausal Women With and Without Metabolic Syndrome.

Christopher E Kline, Martica H Hall, Daniel J Buysse, Conrad P Earnest, Timothy S Church

Open access · greenAbstract read
In one paragraph

Article in Metabolic syndrome and related disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Christopher E Kline1 Department of Health and Physical Activity, Physical Activity and Weight Management Research Center, University of Pittsburgh , Pittsburgh, Pennsylvania.
Martica H Hall2 Department of Psychiatry, University of Pittsburgh , Pittsburgh, Pennsylvania.
Daniel J Buysse2 Department of Psychiatry, University of Pittsburgh , Pittsburgh, Pennsylvania.
Conrad P Earnest3 Department of Health and Kinesiology, Exercise and Sports Nutrition Laboratory, Texas A&M University , College Station, Texas.
Timothy S Church4 ACAP Health , Dallas, Texas.
University of Pittsburgh · USTexas A&M University · USUniversity of Texas Health Science Center at Dallas · US

Funding

A Novel Risk Factor for Cardiovascular Disease: The Insomnia-Short Sleep PhenotypK23HL118318 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KLINE, CHRISTOPHER EDWARD · 2014 to 2018
$776k
NHLBI NIH HHS K23 HL118318
6 · The paper itself

Abstract

backgroundPoor sleep quality has previously been shown to be related to insulin resistance in apparently healthy adults. However, it is unclear whether an association between sleep quality and insulin resistance exists among adults with metabolic syndrome (MetS).

methodsParticipants included 347 overweight/obese postmenopausal women without type 2 diabetes (age: 57.5 ± 6.5 years; body mass index [BMI]: 31.7 ± 3.7 kg/m

resultsWomen with the worst sleep quality had significantly higher HOMA2-IR values than women in all other quartiles (P ≤ 0.05 for each), and women with MetS had significantly higher HOMA2-IR values than women without MetS (P < 0.0001), but the relationship between sleep quality and HOMA2-IR did not differ between those with or without MetS (P = 0.26). Women with MetS in the worst quartile of sleep quality had higher HOMA2-IR values than all other women (P < 0.02). Taking >30 min to fall asleep, frequent restless sleep, and frequent daytime drowsiness were each related to higher HOMA2-IR values (each P < 0.04).

conclusionsSleep quality is an important correlate of insulin resistance in postmenopausal women with and without MetS. Intervention studies are needed to determine whether improving sleep improves insulin resistance in populations at elevated cardiometabolic risk.

Indexed as

Insulin ResistanceSleepAgedBlood GlucoseBody Mass IndexCardiovascular DiseasesCross-Sectional StudiesExerciseFemaleHumansInsulinMetabolic SyndromeMiddle AgedObesityOverweightPostmenopauseBlood GlucoseInsulininsulin resistancemetabolic syndromepostmenopausalsleep quality

Identifiers

PMID29649378
PMCPMC5931175
OpenAlexW2794926471

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.