ArticlePloS one2018
Prediction of lateral pelvic lymph node metastasis in patients with locally advanced rectal cancer with preoperative chemoradiotherapy: Focus on MR imaging findings.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 4 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 4 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Diagnostic performance of magnetic resonance imaging for lateral pelvic lymph node metastasis in patients with rectal carcinoma: a meta-analysis and systematic review.Diagnostic and interventional radiology (Ankara, Turkey) · 2025Pooled it
- Risk factors for lateral pelvic lymph node metastasis in patients with lower rectal cancer: a systematic review and meta-analysis.Frontiers in oncology · 2023Pooled it
- Lateral Pelvic Lymph Node Metastases in Rectal Cancer: A Systematic Review.World journal of surgery · 2019Pooled it
- Diagnostic accuracy of magnetic resonance imaging and computed tomography for lateral lymph node metastasis in rectal cancer: a systematic review and meta-analysis.International journal of clinical oncology · 2019Pooled it
- MRI features of lateral lymph nodes predicting lateral local recurrence and prognostic impact of lateral lymph node dissection in low rectal cancer.European radiology · 2026Article
- The significance of MRI-detected lateral lymph node metastasis in rectal cancer on local recurrence and survival-A nationwide cohort study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026Observational
- Quantitative Dynamic Contrast-Enhanced Magnetic Resonance Imaging and Positron Emission Tomography (PET) for Distinguishing Metastatic Lymph Nodes from Nonmetastatic Among Patients with Rectal Cancer: A Systematic Review and Meta-Analysis.World journal of nuclear medicine · 2025Article
- Positive lateral lymph node turned negative after neoadjuvant therapy-surgery or observation?Techniques in coloproctology · 2025Review
- Who is a candidate at the initial presentation? Prediction of positive lateral lymph node and survival after dissection.Techniques in coloproctology · 2025Review
- The role of lateral pelvic lymph node dissection in advanced rectal cancer: a review of current evidence and outcomes.Annals of coloproctology · 2024Review
- Management of internal iliac and obturator lymph nodes in mid-low rectal cancer.World journal of surgical oncology · 2024Review
- Current perspectives on the management of lateral pelvic lymph nodes in rectal cancer.World journal of clinical oncology · 2023Review
- Significant improvement after training in the assessment of lateral compartments and short-axis measurements of lateral lymph nodes in rectal cancer.European radiology · 2023Article
- MRI-based radiomics to predict neoadjuvant chemoradiotherapy outcomes in locally advanced rectal cancer: A multicenter study.Clinical and translational radiation oncology · 2023Article
- Role of one-step nucleic acid amplification in colorectal cancer lymph node metastases detection.World journal of gastroenterology · 2022Review
- Does neoadjuvant chemoradiotherapy increase the effect of lateral lymph node dissection on urogenital function?Translational cancer research · 2022Article
- Lateral lymph node dissection and urogenital function with and without neoadjuvant treatment.Translational cancer research · 2022Article
- Clinical implication and management of rectal cancer with clinically suspicious lateral pelvic lymph node metastasis: A radiation oncologist's perspective.Frontiers in oncology · 2022Review
- Development and External Validation of a Preoperative Nomogram for Predicting Lateral Pelvic Lymph Node Metastasis in Patients With Advanced Lower Rectal Cancer.Frontiers in oncology · 2022Article
- Management, treatment and prognostic significance of lateral lymph node metastases in rectal cancer-a regional cohort study.International journal of colorectal disease · 2021Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate the predictive factors for lateral pelvic lymph node (LPLN) metastasis in patients with locally advanced rectal cancer treated with preoperative chemoradiotherapy (CRT). MATERIALS AND
methodsFifty-seven patients with locally advanced rectal cancer and LPLNs larger than 5 mm underwent LPLN dissection (LPLD) after preoperative CRT. The MRI findings, including the apparent diffusion coefficient value and LPLN size reduction rate before/after CRT; clinical factors; and pathologic results were evaluated to identify the predictive factors associated with LPLN metastasis.
resultsLPLN metastasis was confirmed in 23 patients (40.4%). Metastasis was significantly higher in LPLNs with multiplicity, short-axis diameter ≥8 mm before CRT, short-axis diameter >5 mm after CRT, size reduction rate ≤33.3%, heterogeneous signal intensity, and irregular margin (P<0.05) on MR. Multivariable analysis showed that pre-CRT short-axis diameter of LPLNs ≥8 mm, size reduction rate ≤33.3%, and heterogeneous signal intensity were independently associated with LPLN metastasis.
conclusionsThe size and signal intensity of LPLN before and after CRT are useful MRI findings to predict LPLN metastasis and are helpful to determine the indications for LPLD.
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