ReviewInternational journal of molecular sciences2018
Nanocoatings for Chronic Wound Repair-Modulation of Microbial Colonization and Biofilm Formation.
Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 132 citations in OpenAlex.
- Preclinical evaluation of silver-doped copper carbonate nanoparticles for antidiabetic and wound healing effects in mice.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Evaluating 3D-Patch Efficacy in Wound Healing Using the Medicinal LeechNanomaterials (Basel, Switzerland) · 2026Article
- Cytokine and chemokine dysregulation by microbial biofilm components: mechanisms and clinical implications.Archives of microbiology · 2026Review
- Population structure, antimicrobial resistance, and virulence factors of diabetic foot-associatedMicrobiology spectrum · 2026Article
- Diabetic Wound Healing: Mechanism and Treatment Strategies with a Special Focus on Angiogenesis.Current drug research reviews · 2026Review
- Article
- Antibacterial Composites Based on Alginate/Egg White and ZnO Nanoparticles with the Addition of Essential Oils.Gels (Basel, Switzerland) · 2025Article
- The relationship between the skin microbiome and probiotics in the healing of burn injuries.Folia microbiologica · 2025Review
- Nanozyme-driven multifunctional dressings: moving beyond enzyme-like catalysis in chronic wound treatment.Military Medical Research · 2025Review
- Evaluation of the antibacterial properties of four bioactive biomaterials for chronic wound management.Future microbiology · 2025Article
- Polymer-Based Wound Dressings Loaded with Essential Oil for the Treatment of Wounds: A Review.Pharmaceuticals (Basel, Switzerland) · 2024Review
- Nanostructured Coatings Based on Graphene Oxide for the Management of Periprosthetic Infections.International journal of molecular sciences · 2024Article
- New strategies for sterilization and preservation of fresh fish skin grafts.Scientific reports · 2024Article
- An Overview of Recent Developments in the Management of Burn Injuries.International journal of molecular sciences · 2023Review
- Probiotics in Orthopedics: From Preclinical Studies to Current Applications and Future Perspective.Microorganisms · 2023Review
- Antimicrobial Biomaterials for Chronic Wound Care.Pharmaceutics · 2023Review
- Synergistic Antimicrobial Activity of Magnetite and Vancomycin-Loaded Mesoporous Silica Embedded in Alginate Films.Gels (Basel, Switzerland) · 2023Article
- Larval Therapy and Larval Excretions/Secretions: A Potential Treatment for Biofilm in Chronic Wounds? A Systematic Review.Microorganisms · 2023Review
- Metal-Phenolic Networks for Chronic Wounds Therapy.International journal of nanomedicine · 2023Review
- Cell-free supernatant of probiotic bacteria exerted antibiofilm and antibacterial activities againstFrontiers in pharmacology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Wound healing involves a complex interaction between immunity and other natural host processes, and to succeed it requires a well-defined cascade of events. Chronic wound infections can be mono- or polymicrobial but their major characteristic is their ability to develop a biofilm. A biofilm reduces the effectiveness of treatment and increases resistance. A biofilm is an ecosystem on its own, enabling the bacteria and the host to establish different social interactions, such as competition or cooperation. With an increasing incidence of chronic wounds and, implicitly, of chronic biofilm infections, there is a need for alternative therapeutic agents. Nanotechnology shows promising openings, either by the intrinsic antimicrobial properties of nanoparticles or their function as drug carriers. Nanoparticles and nanostructured coatings can be active at low concentrations toward a large variety of infectious agents; thus, they are unlikely to elicit emergence of resistance. Nanoparticles might contribute to the modulation of microbial colonization and biofilm formation in wounds. This comprehensive review comprises the pathogenesis of chronic wounds, the role of chronic wound colonization and infection in the healing process, the conventional and alternative topical therapeutic approaches designed to combat infection and stimulate healing, as well as revolutionizing therapies such as nanotechnology-based wound healing approaches.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.