Evidence map›Paper›PMID 29648856›Full record

Trial reportJournal of consulting and clinical psychology2018

Treatment expectancy and working alliance in pharmacotherapy as predictors of outcomes in complicated grief.

Elizabeth M Goetter, Christine M Mauro, Xin Qiu, Natalia A Skritskaya, Charles F Reynolds, Sidney Zisook, M Katherine Shear, Naomi M Simon

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of consulting and clinical psychology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Elizabeth M GoetterDepartment of Psychiatry.
Christine M MauroMailman School of Public Health, Columbia University.
Xin QiuMailman School of Public Health, Columbia University.
Natalia A SkritskayaColumbia School of Social Work.
Charles F ReynoldsGeriatric Psychiatry and Graduate School of Public Health, University of Pittsburgh School of Medicine.
Sidney ZisookDepartment of Psychiatry, University of California, San Diego.
M Katherine ShearColumbia School of Social Work.
Naomi M SimonDepartment of Psychiatry, Massachusetts General Hospital.
Columbia University · USMassachusetts General Hospital · USUniversity of California, San Diego · US

Funding

TRAUMATIC GRIEF TREATMENT--A RANDOMIZED CONTROLLED STUDYR01MH060783 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DUAN, NAIHUA, SHEAR, M KATHERINE · 2000 to 2016
$4.0M
2/4-Optimizing Treatment of Complicated GriefR01MH085308 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI SIMON, NAOMI M · 2009 to 2013
$2.0M
3/4-Optimizing Complicated Grief TherapyR01MH085288 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REYNOLDS, CHARLES F. · 2009 to 2013
$1.7M
4/4-Optimizing Treatment of Complicated GriefR01MH085297 · NIMH · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI ZISOOK, SIDNEY · 2009 to 2013
$1.6M
American Foundation for Suicide PreventionDepartment of DefenseHighland Street FoundationNIH HHSNIMH NIH HHS R01 MH060783NIMH NIH HHS R01 MH085288NIMH NIH HHS R01 MH085297NIMH NIH HHS R01 MH085308
6 · The paper itself

Abstract

objectiveNonspecific factors, such as treatment outcome expectancy and working alliance, can influence treatment outcome. No studies to date have examined the role of expectancy and alliance on pharmacotherapy outcomes in individuals with complicated grief (CG).

methodThis secondary analysis of a larger randomized, control trial (RCT) examined the relationship between pharmacotherapy expectancy and alliance on treatment outcome in adults with CG who were participating in a multisite, double-blind, RCT examining the efficacy of citalopram and complicated grief treatment (CGT). Participants (n = 202) were randomized to one of four treatment conditions: citalopram (CIT), placebo (PBO), CGT + citalopram (CGT + CIT), or CGT + placebo (CGT + PBO).

resultsPharmacotherapy outcome expectancy and working alliance were higher among individuals randomized to CGT + CIT and CGT + PBO compared with CIT or PBO without CGT. Pharmacotherapy outcome expectancy was higher at Week 2 among individuals who ultimately responded to treatment compared with those who did not and among those who remained in treatment compared with those who dropped out. In contrast, working alliance did not correlate with dropout or treatment outcomes in pharmacotherapy.

conclusionsExpectancy for medication was higher among individuals randomized to receive CGT. Clinicians should assess symptoms and expectancies in the first weeks of treatment because these could be early markers of drop out and treatment response. (PsycINFO Database Record

Indexed as

GriefTherapeutic AllianceAdultAgedAntidepressive Agents, Second-GenerationCitalopramCombined Modality TherapyDouble-Blind MethodFemaleHumansMaleMiddle AgedPsychotherapyTreatment OutcomeAntidepressive Agents, Second-GenerationCitalopram

Identifiers

PMID29648856
PMCPMC5901890
OpenAlexW2797132033

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.