Observational studyArthritis care & research2019
Quantitative Signal Intensity Alteration in Infrapatellar Fat Pad Predicts Incident Radiographic Osteoarthritis: The Osteoarthritis Initiative.
Observational study in Arthritis care & research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Correlation study of infrapatellar fat pad EI in assessing clinical symptoms of knee osteoarthritis.Scientific reports · 2026Article
- The infrapatellar fat pad mediates environmental exposure for clinical outcomes in knee osteoarthritis.Osteoarthritis and cartilage open · 2026Article
- Radiomic features of infrapatellar fat pad are associated with knee symptoms and radiographic post-traumatic osteoarthritis at 10+ years after anterior cruciate ligament reconstruction.Osteoarthritis imaging · 2025Article
- Comprehensive comparative analysis of infrapatellar fat pad morphologies in a longitudinal knee osteoarthritis exploratory study: new insights into its role as an independent prognostic marker.Arthritis research & therapy · 2025Article
- Infrapatellar fat pad as a source of biomarkers and therapeutic target for knee osteoarthritis.Arthritis research & therapy · 2025Review
- Predicting incident radiographic knee osteoarthritis through quantitative meniscal lesion parameters: data from the osteoarthritis initiative.BMC musculoskeletal disorders · 2024Article
- Sonographic Characterization of the Pericruciate Fat Pad with the Use of Compression Elastography-A Cross-Sectional Study among Healthy and Post-Injured Patients.Journal of clinical medicine · 2024Article
- Ultrasound assessment of the infrapatellar fat pad can detect Hoffa-synovitis in patients following anterior cruciate ligament reconstruction: A pilot study.Osteoarthritis imaging · 2024Article
- Anterior Tibiotalar Fat Pad Involvement in Ankle Osteoarthritis: MRI Features in Patients 1 Year After a Lateral Ankle Sprain.Cartilage · 2023Observational
- Quantitative evaluation of the infrapatellar fat pad in knee osteoarthritis: MRI-based radiomic signature.BMC musculoskeletal disorders · 2023Article
- Correlation between the Signal Intensity Alteration of Infrapatellar Fat Pad and Knee Osteoarthritis: A Retrospective, Cross-Sectional Study.Journal of clinical medicine · 2023Article
- Quantitative infrapatellar fat pad signal intensity alteration as an imaging biomarker of knee osteoarthritis progression.RMD open · 2023Article
- Prediction model for knee osteoarthritis using magnetic resonance-based radiomic features from the infrapatellar fat pad: data from the osteoarthritis initiative.Quantitative imaging in medicine and surgery · 2023Article
- Longitudinal association of infrapatellar fat pad signal intensity alteration with biochemical biomarkers in knee osteoarthritis.Rheumatology (Oxford, England) · 2022Article
- An Open Debate on the Morphological Measurement Methodologies of the Infrapatellar Fat Pad to Determine Its Association with the Osteoarthritis Process.Current rheumatology reports · 2022Review
- Epidemiology of osteoarthritis.Osteoarthritis and cartilage · 2022Review
- Signal intensity alteration and maximal area of pericruciate fat pad are associated with incident radiographic osteoarthritis: data from the Osteoarthritis Initiative.European radiology · 2022Article
- Quantitative volume and dynamic contrast-enhanced MRI derived perfusion of the infrapatellar fat pad in patellofemoral pain.Quantitative imaging in medicine and surgery · 2021Article
- Infrapatellar Fat Pad Gene Expression and Protein Production in Patients with and without Osteoarthritis.International journal of molecular sciences · 2020Article
- Quantitative DCE-MRI demonstrates increased blood perfusion in Hoffa's fat pad signal abnormalities in knee osteoarthritis, but not in patellofemoral pain.European radiology · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
objectiveTo determine whether infrapatellar fat pad (IPFP) signal intensity measures are predictive of incident radiographic osteoarthritis (ROA) over 4 years in the Osteoarthritis Initiative study.
methodsCase knees (n = 355), as defined by incident ROA, were matched 1:1 with control knees, according to sex, age, and radiographic status. T2-weighted magnetic resonance images were assessed at P0 (the visit when incident ROA was observed on a radiograph), P1 (1 year prior to P0), and baseline and used to assess IPFP signal intensity semiautomatically. Conditional logistic regression analyses were performed to assess the risk of incident ROA associated with IPFP signal intensity alteration, after adjustment for covariates.
resultsThe mean age of the participants was 60.2 years, and most (66.7%) were female and overweight (mean body mass index 28.3 kg/m
conclusionThe quantitative segmentation of high signal intensity in the IPFP observed in our study confirms the findings of previous work based on semiquantitative assessment, suggesting the predictive validity of semiquantitative assessment of IPFP high signal intensity. The IPFP high signal intensity alteration could be an important imaging biomarker to predict the occurrence of ROA.
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