Evidence map›Paper›PMID 29648687›Full record

ArticleArthritis care & research2019

Lipid Testing and Statin Prescriptions Among Medicaid Recipients With Systemic Lupus Erythematosus or Diabetes Mellitus and the General Medicaid Population.

Sarah K Chen, Medha Barbhaiya, Michael A Fischer, Hongshu Guan, Tzu-Chieh Lin, Candace H Feldman, Brendan M Everett, Karen H Costenbader

Abstract read
In one paragraph

Article in Arthritis care & research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Sarah K ChenBrigham and Women's Hospital, Boston, Massachusetts.ORCID 0000-0002-8206-597X
Medha BarbhaiyaHospital for Special Surgery, New York, New York.
Michael A FischerBrigham and Women's Hospital, Boston, Massachusetts.
Hongshu GuanBrigham and Women's Hospital, Boston, Massachusetts.
Tzu-Chieh LinBrigham and Women's Hospital, Boston, Massachusetts.ORCID 0000-0002-8333-7666
Candace H FeldmanBrigham and Women's Hospital, Boston, Massachusetts.
Brendan M EverettBrigham and Women's Hospital, Boston, Massachusetts.
Karen H CostenbaderBrigham and Women's Hospital, Boston, Massachusetts.
Brigham and Women's Hospital · USHospital for Special Surgery · US

Funding

Sociodemographic Disparities in SLE Incidence: Behavioral and Psychosocial FactorsR01AR057327 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI COSTENBADER, KAREN H · 2009 to 2019
$6.2M
Cardiovascular Disease Epidemiology in Patients with LupusK24AR066109 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI COSTENBADER, KAREN H · 2014 to 2023
$1.7M
Avoidable Acute Care Use among Patients with LupusK23AR071500 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI FELDMAN, CANDACE HILLARY · 2017 to 2021
$945k
Biogen-IdecGlaxoSmithKlineLupus Foundation of AmericaMerckNIAMS NIH HHS K23 AR071500NIAMS NIH HHS K24 AR066109NIAMS NIH HHS R01 AR057327PfizerRheumatology Research Foundation
6 · The paper itself

Abstract

objectiveCardiovascular disease (CVD) risks in systemic lupus erythematosus (SLE) are similar to those in diabetes mellitus (DM). We investigated whether the numbers of lipid tests and statin prescriptions in patients with SLE are comparable with those in patients with DM and those in individuals without either disease.

methodsUsing Analytic eXtract files from 29 states for 2007-2010, we identified a cohort of US Medicaid beneficiaries, ages 18-65 years, with prevalent SLE. Each SLE patient was matched for age and sex with 2 patients with DM and 4 individuals in the general Medicaid population who did not have either SLE or DM. We compared the proportions of patients in each cohort who received ≥1 lipid test and ≥1 statin prescription during 1-year follow-up. We used multivariable logistic regression to calculate the odds of lipid testing and receiving prescriptions for statins and conditional logistic regression to compare the matched cohorts.

resultsWe identified 3 Medicaid cohorts: 25,950 patients with SLE, 51,900 patients with DM, and 103,800 Medicaid recipients without either condition. In these cohorts, lipid testing was performed in 24% of patients in the SLE group, 43% of patients in the DM group, and 16% of individuals in the group with neither condition, and statin prescriptions were dispensed in 11%, 33%, and 7% of these groups, respectively. SLE patients were 66% less likely (odds ratio [OR] 0.34, 95% confidence interval [95% CI] 0.34-0.35) to have lipid tests and 82% less likely (OR 0.18, 95% CI 0.18-0.18) to fill a statin prescription compared with DM patients. SLE patients were also less likely (OR 0.89, 95% CI 0.84-0.94) to fill a statin prescription compared with individuals in the general Medicaid population.

conclusionDespite having an elevated risk of CVD, SLE patients received less lipid testing and received fewer statin prescriptions compared with age- and sex-matched DM patients and individuals in the general Medicaid population; this gap should be a target for improvement.

Indexed as

Population SurveillanceAdolescentAdultAgedCohort StudiesDiabetes MellitusDrug PrescriptionsFemaleFollow-Up StudiesHematologic TestsHumansHydroxymethylglutaryl-CoA Reductase InhibitorsLipidsLupus Erythematosus, SystemicMaleMedicaidHydroxymethylglutaryl-CoA Reductase InhibitorsLipids

Identifiers

PMID29648687
PMCPMC6185821
OpenAlexW2797759878

What OpenQuestion holds

Texttitle and abstract
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.