Evidence map›Paper›PMID 29644529›Full record

ArticleMolecular and cellular biochemistry2018

Effects of increased accumulation of doxorubicin due to emodin on efflux transporter and LRP1 expression in lung adenocarcinoma and colorectal carcinoma cells.

Vidhya V Iyer, P Yoga Priya, Jeipreeti Kangeyavelu

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular and cellular biochemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Synergistic Interactions of Anthraquinones with Conventional Cancer Therapies.Combinatorial chemistry & high throughput screening · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Vidhya V IyerSchool of Biosciences and Technology, Vellore Institute of Technology, Vellore, Tamil Nadu, 632 014, India. vi99_mc@yahoo.com.ORCID http://orcid.org/0000-0002-5927-1927
P Yoga PriyaSchool of Biosciences and Technology, Vellore Institute of Technology, Vellore, Tamil Nadu, 632 014, India.
Jeipreeti KangeyaveluSchool of Biosciences and Technology, Vellore Institute of Technology, Vellore, Tamil Nadu, 632 014, India.
Indian Institute of Technology Bombay · INMadurai Kamaraj University · INVellore Institute of Technology University · IN

Funding

Science and Engineering Research Board SB/YS/LS-138/2013
6 · The paper itself

Abstract

Treatment with doxorubicin (dox) and emodin, separately and together, under normoxic and hypoxia-like conditions induced by CoCl

Indexed as

DoxorubicinEmodinA549 CellsAdenocarcinoma of LungCarrier ProteinsColorectal NeoplasmsHumansLow Density Lipoprotein Receptor-Related Protein-1Lung NeoplasmsNeoplasm ProteinsCarrier ProteinsDoxorubicinEmodinLow Density Lipoprotein Receptor-Related Protein-1LRP1 protein, humanNeoplasm ProteinsAccumulationCancerDoxorubicinEfflux transporterEmodinLRP1

Identifiers

PMID29644529
OpenAlexW2800697925

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.