Evidence map›Paper›PMID 29644471›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2018

Assessment of psychological distress among Asian adolescents and young adults (AYA) cancer patients using the distress thermometer: a prospective, longitudinal study.

Alexandre Chan, Eileen Poon, Wei Lin Goh, Yanxiang Gan, Chia Jie Tan, Kelvin Yeo, Annabelle Chua, Magdalene Chee, Yi Chye Law, Nagavalli Somasundaram and 9 more

Abstract read
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In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 49 citations in OpenAlex.

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  4. Distress screening and management for adolescents and young adults: 2022 NCI community oncology program landscape assessment.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 2 institutions in 1 country.

Alexandre ChanDepartment of Pharmacy, National University of Singapore, Blk S4A Level 3, 18 Science Drive 4, Singapore, 117543, Singapore. phaac@nus.edu.sg.
Eileen PoonDivision of Medical Oncology, 11 Hospital Drive, National Cancer Centre Singapore, Singapore, 169610, Singapore.
Wei Lin GohDivision of Medical Oncology, 11 Hospital Drive, National Cancer Centre Singapore, Singapore, 169610, Singapore.
Yanxiang GanDepartment of Pharmacy, National Cancer Centre Singapore, Singapore, Singapore.
Chia Jie TanDepartment of Pharmacy, National University of Singapore, Blk S4A Level 3, 18 Science Drive 4, Singapore, 117543, Singapore.
Kelvin YeoDepartment of Pharmacy, National University of Singapore, Blk S4A Level 3, 18 Science Drive 4, Singapore, 117543, Singapore.
Annabelle ChuaDepartment of Pharmacy, National University of Singapore, Blk S4A Level 3, 18 Science Drive 4, Singapore, 117543, Singapore.
Magdalene CheeDivision of Medical Oncology, 11 Hospital Drive, National Cancer Centre Singapore, Singapore, 169610, Singapore.
Yi Chye LawDivision of Medical Oncology, 11 Hospital Drive, National Cancer Centre Singapore, Singapore, 169610, Singapore.
Nagavalli SomasundaramDivision of Medical Oncology, 11 Hospital Drive, National Cancer Centre Singapore, Singapore, 169610, Singapore.
Ravindran KanesvaranDivision of Medical Oncology, 11 Hospital Drive, National Cancer Centre Singapore, Singapore, 169610, Singapore.
Quan Sing NgDivision of Medical Oncology, 11 Hospital Drive, National Cancer Centre Singapore, Singapore, 169610, Singapore.
Chee Kian ThamDivision of Medical Oncology, 11 Hospital Drive, National Cancer Centre Singapore, Singapore, 169610, Singapore.
Chee Keong TohDivision of Medical Oncology, 11 Hospital Drive, National Cancer Centre Singapore, Singapore, 169610, Singapore.
Soon Thye LimDivision of Medical Oncology, 11 Hospital Drive, National Cancer Centre Singapore, Singapore, 169610, Singapore.
Miriam TaoDivision of Medical Oncology, 11 Hospital Drive, National Cancer Centre Singapore, Singapore, 169610, Singapore.
Tiffany TangDivision of Medical Oncology, 11 Hospital Drive, National Cancer Centre Singapore, Singapore, 169610, Singapore.
Richard QuekDivision of Medical Oncology, 11 Hospital Drive, National Cancer Centre Singapore, Singapore, 169610, Singapore.
Mohamad FaridDivision of Medical Oncology, 11 Hospital Drive, National Cancer Centre Singapore, Singapore, 169610, Singapore. mohamad.farid@singhealth.com.sg.
National Cancer Centre Singapore · SGNational University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSince few studies have investigated whether the Distress Thermometer (DT) in Asian adolescent and young adult (AYA) cancer patients (between 15 and 39 years), we investigated the appropriateness of the DT as a screening tool for psychological symptom burden in these AYA patients and to evaluate AYA patients' distress across a trajectory of three time points longitudinally over a 6-month period.

methodsThis was a prospective, longitudinal study. Recruited Asian AYA patients were diagnosed with lymphomas, sarcomas, primary brain malignancies, or germ cell tumors. Patients completed the DT, PedsQL Generic Core Scales, and the Rotterdam Symptom Checklist. Data were analyzed using STATA version 15.

resultsApproximately half of the patients experienced clinically significant DT distress (distress score ≥ 4) early in their cancer journey with 43.1% patients presenting with distress at time of diagnosis and 47.7% patients 1 month after diagnosis. Among AYA patients > 24 years old, worry (68.3%), insurance/financial issues (61%), treatment decisions (43.9%), work/school issues (41.5%), nervousness (41.5%), and sadness (41.5%) were the top five identified problems. On the other hand, the top five identified problems among AYA ≤ 24 years were worry (54.2%), nervousness (41.7%), bathing/dressing problems (37.5%), work/school issues (33.3%), and fatigue (33.3%). DT scores were significantly associated with certain psychological symptom burden items such as worry (p < 0.001), depressed mood (p = 0.020), and nervousness (p = 0.015).

conclusionThe DT is a useful screening tool for psychological distress in AYA cancer patients with clinically significant distress being identified in the early phases of the cancer journey.

Indexed as

AdolescentAdultAsian PeopleFemaleHumansLongitudinal StudiesMaleMass ScreeningNeoplasmsProspective StudiesStress, PsychologicalYoung AdultAdolescent and young adultsCancerPsychological distress

Identifiers

PMID29644471
OpenAlexW2797584159

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.