Evidence map›Paper›PMID 29644457›Full record

ArticleCurrent genetics2018

An interplay between Shugoshin and Spo13 for centromeric cohesin protection and sister kinetochore mono-orientation during meiosis I in Saccharomyces cerevisiae.

Gunjan Mehta, Guhan Kaliyaperumal Anbalagan, Akhilendra Pratap Bharati, Purna Gadre, Santanu Kumar Ghosh

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Article in Current genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Gunjan MehtaNational Cancer Institute, National Institutes of Health, 41 Medlars Drive, Bethesda, MD, 20892, USA.ORCID http://orcid.org/0000-0003-2896-3039
Guhan Kaliyaperumal AnbalaganDepartment of Biosciences and Bioengineering, Indian Institute of Technology, Bombay, Powai, Mumbai, 400076, India.ORCID http://orcid.org/0000-0001-7823-7153
Akhilendra Pratap BharatiDepartment of Biosciences and Bioengineering, Indian Institute of Technology, Bombay, Powai, Mumbai, 400076, India.
Purna GadreB231, Department of Biological Sciences, Tata Institute of Fundamental Research, Mumbai, 400005, India.
Santanu Kumar GhoshDepartment of Biosciences and Bioengineering, Indian Institute of Technology, Bombay, Powai, Mumbai, 400076, India. santanughosh@iitb.ac.in.
Indian Institute of Technology Bombay · INNational Institutes of Health · USTata Institute of Fundamental Research · IN

Funding

Board of Research in Nuclear Sciences 37(1)/14/30/2015/BRNSCouncil of Scientific and Industrial Research 20-6/2009(i)EU-IV/329667Department of Biotechnology, Ministry of Science and Technology BT/PR13962/BRB/10/798/2010Department of Science and Technology, Ministry of Science and Technology DST/INSPIRE Fellowship/2015/IF150117Department of Science and Technology, Ministry of Science and Technology SR/SO/BB-57/2009Science and Engineering Research Board PDF/2016/000937
6 · The paper itself

Abstract

Meiosis is a specialized cell division process by which haploid gametes are produced from a diploid mother cell. Reductional chromosome segregation during meiosis I (MI) is achieved by two unique and conserved events: centromeric cohesin protection (CCP) and sister kinetochore mono-orientation (SKM). In Saccharomyces cerevisiae, a meiosis-specific protein Spo13 plays a role in both these centromere-specific events. Despite genome-wide association of Spo13, we failed to detect its function in global processes such as cohesin loading, cohesion establishment and homologs pairing. While Shugoshin (Sgo1) and protein phosphatase 2A (PP2A

Indexed as

Chromosome SegregationMeiosisAurora KinasesCell Cycle ProteinsCentromereChromosomal Proteins, Non-HistoneChromosomes, FungalCohesinsGenome, FungalKinetochoresNuclear ProteinsProton PumpsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsAurora KinasesCell Cycle ProteinsChromosomal Proteins, Non-HistoneCohesinsIPL1 protein, S cerevisiaeMam1 protein, S cerevisiaeNuclear ProteinsPPA2 protein, S cerevisiaeProton PumpsSaccharomyces cerevisiae ProteinsSgo1 protein, S cerevisiaeSPO13 protein, S cerevisiaeCohesinMeiosisMono-orientationSaccharomyces cerevisiaeSgo1Spo13

Identifiers

PMID29644457
OpenAlexW2797491295

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.